Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID35100	Osimertinib	GSE70138	HA1E	Human	24h	0.123457uM	EID0160

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	ZNF586; ZNF551; ZNF211; IKZF5; ZNF134; EMX2; ZNF419; SP100; CCDC59; DDX5; ZNF430; NR1D2; TRIM28; HMGB1; ENY2; BCLAF1; ZBTB11; NFYB; KLF13; ZFHX3; BBX; AES; ZHX2; TCF12; ZNF304; ZNF227; ARNTL2; SP110; AFF1; AGO2; PEG3; ZFPM2; MYRF; MED1; DDIT3; SFPQ; EPAS1; IRF7; GATA6; BRD2; RUNX1; SMARCA1; AHR; ZNF83; AEBP1; ZNF281; BCL11B; CTR9; YBX3; TRIM22; CERS6; SOX11; ZNF91; SP140L; KDM5D; ZBED2; OSR2; FOXO1; BHLHE41; ERG; NKX3-1; HMGA1; DACH1; TOX3; IKZF1; MEIS2
Down-regulation	36	KLF4; FOSB; TDP2; DLX2; HOXB7; SATB2; ZNF217; POU2AF1; STAT3; HLTF; TWIST1; ID3; EN1; TRIP6; WWC1; IRX5; BCL11A; CEBPB; IRF8; MYBL1; CITED2; TCF7L1; CUX2; ATF3; TSC22D1; TFAP2C; MYCN; ZIC1; MSX1; KLF5; SOX9; E2F2; SNAI2; NFIB; ESR1; ADRB2