Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID35096	Osimertinib	GSE70138	HA1E	Human	24h	10uM	EID0160

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	MNAT1; TSC22D3; HBP1; SREBF2; RBFOX2; DACH1; NRBF2; ATF5; PBX3; LPIN2; SIX2; GLI3; PHF20; MED21; KLF11; HDAC5; ZNF226; CUX2; STAT1; RSF1; TRAK1; ERBB4; ERBB2; SALL1; PIAS3; RYBP; ZNF516; TRPS1; THAP10; NFYB; CREBL2; TOB1; ZSCAN18; GTF2IRD1; PBX1; ARNTL; HMGA1; HDAC9; MEF2A; ZFP36L2; FOXA2; INSR; JARID2; ELK3; TRIM22; MYRF; WWP1; CERS6; MEIS1; HOXB2; CTBP2; SMARCA1; MECOM; IFI16; BTG1; CBX6; IRX5; ZNF331; ESR1; ZFP36L1; KLF5; AHR; NFATC4; EPAS1; STAT3; MEIS2; IKZF1; SOX9; E2F2
Down-regulation	61	MYCBP; JUN; CCNA2; GTF2A2; XBP1; ECD; ZNF124; RUVBL1; HIRA; NOC2L; MLXIP; SOX10; SETD3; TCF7; E2F8; CITED1; TCF4; DNAJC2; HOXB7; TAF1D; PHF8; DPF2; PURA; NFAT5; HOXB13; KLF2; ZNF593; BATF3; ZNF587; YWHAB; ENO1; TGFB1I1; RBM14; POU4F1; OLIG2; MSX1; TGIF2; LOXL2; LMCD1; PTTG1; TERF2; NKX3-1; LEF1; FLNA; FOSB; CBFA2T3; SKI; ELF5; TBX3; BAZ1A; ID3; ATF3; RUNX1; PITX1; YBX3; POU2AF1; TXNIP; KDM5D; ERG; HHEX; ADRB2