Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID34818	Mitoxantrone	GSE70138	HA1E	Human	24h	10uM	EID0158

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	NFATC3; VPS72; GATA2; CEBPD; TBX19; KAT2B; WDR77; RUVBL1; TFDP1; TBX2; SPDEF; HIF3A; HMGA1; ZNF219; DNMT1; CREBL2; FOXF2; TSC22D3; SREBF2; NR0B2; IRF6; KDM5D; ARNT2; SUPT4H1; ESRRG; CAMTA2; SRCAP; TRIM24; PHF1; SLC2A4RG; CHD3; ZEB1; MYCL; KAT2A; HIPK2; MTA1; CREB3L2; BPTF; BCL11A; KAT6B; CNBP; ZNF532; NR0B1; GRHL2; CREM; VDR; VGLL1; ZNF467; HIPK1; EN1; IRF8; ZNF586; CLOCK; TXNIP; CSDE1; FOXC1; PEG3; ZNF264; FOS; ZKSCAN1; TCF21; SOX10; PBX3; TBX3; MBD2; MXI1; HLX; FOSB; ERBB4; JUP; FOXF1; OSR2; NR1H2; ETV1; DLX2; ATF3; TRPS1; MYBL1; STAT3
Down-regulation	115	FHL2; XBP1; GMNN; CCNA2; CEBPZ; MYC; NFIL3; NUP62; NRIP1; SUV39H1; BHLHE40; CDK7; SUZ12; NFKBIA; PUF60; SCAND1; TLE1; ID2; RREB1; FOSL1; USP22; PAX8; SOX4; FOXO3; HOXA5; SMAD3; CHD1; RBBP4; ATF4; RBM14; HOXB7; EZH2; HSBP1; SFPQ; FOSL2; CCNC; TGIF1; BCOR; RNF4; SALL1; ZMYM2; HOXA7; ZNF22; EDF1; KLF10; UBE2I; REST; DNMT3B; ADNP; PHF20; SMARCE1; MDM4; HOXB2; CTCF; PREB; IRF2; TAF1D; TERF1; BRD8; CRY1; VEZF1; TRIM32; ZNF292; HMGB1; CTBP2; KLF2; POU2AF1; PQBP1; HOXA10; HMGB2; ZMIZ1; CTR9; SP3; HMGB3; ZNF146; TSC22D1; FLI1; TBL1XR1; DDX17; SMAD7; HOXB6; YWHAB; ZNF302; MYT1L; BNC2; APEX1; MTF2; JARID2; ZNF160; RUVBL2; IRF4; MEOX2; PGR; WT1; ZBTB18; ZNF721; KLF6; SAP30; HOXC6; MED1; BTG1; MYB; ZBTB38; EGR2; AFF1; BHLHE41; TAL1; NR1D2; ZEB2; INSM1; ERG; ID4; E2F2; SOX9; NFKB2