Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID34630	Mitoxantrone	GSE70138	HA1E	Human	24h	10uM	EID0157

Response Information :

Types	Number	Response transcription factors
Up-regulation	187	MAFB; PHF1; ZNF264; ARNT2; ELF5; PAX6; SUPT4H1; NR1H2; THRA; SOHLH2; IRF6; ID1; PPARG; PRDM14; ZNF551; TXNIP; ZBTB17; ZNF224; BAZ2A; MAF; ZNF415; KLF4; TFAP2A; VPS72; WNT4; EN1; CDK9; GATA2; NFATC1; ZNF606; FOXC1; SHOX2; ZNF768; THAP4; MBD4; E4F1; USF2; CREBZF; CBX4; SNAI2; MAPK8IP1; CREB3L2; ZBTB16; L3MBTL1; PNRC1; POU2F2; CXXC1; CUX2; PBX3; ZMYND11; DAXX; TULP4; TCF4; NKX2-5; RUVBL1; NR1I2; CREB1; TWIST1; PPP1R13L; RHOA; MBD1; PTRF; YBX2; ATF6; TOX3; ZNF200; ZNF75D; IRF8; ZNF778; SATB2; ARNT; HLF; ZNF83; ZBTB43; PEX2; TCEB2; HLX; CEBPD; HIPK2; SIRT7; CIR1; BCL6; MED13; KAT2A; IL16; SREBF2; BACH2; ZEB1; SLC2A4RG; CDIP1; ZNF136; SRCAP; ZNF24; ZNF467; CDC5L; ZHX3; SIM1; MEF2C; TFEB; BTG1; ZNF329; DACH1; BPTF; KMT2B; TRPS1; NLK; POU3F2; BCL11A; MBD2; NKX3-2; MXI1; HDAC5; AHR; NFATC3; NR0B2; CITED2; CREBL2; SIM2; CERS6; FOSB; MEOX2; TRIB3; ESRRG; MKL2; ERBB4; CLOCK; ZSCAN18; ZNF107; ZNF711; PRRX1; NPAS2; EMX1; ZKSCAN1; ZNF211; ELK3; PBX1; LHX2; HOXD11; PAX5; BRD2; FOS; TOB1; CNBP; HSF2; ZNF177; KLF5; ZNF423; ZNF12; CARHSP1; SSBP2; TGFB1; VGLL1; HIVEP2; OLIG2; KLF13; CRYM; ZNF665; FOXO1; NR3C2; ZIC1; HEY2; ZBED2; MITF; MNDA; TRAK1; SOX11; NR2E1; ZBTB20; EGR2; ADRB2; IRX5; DLX2; NKX2-2; PEG3; ZFP36L1; NR2F1; LIN28A; FOXG1; MYBL1; LOXL2; TLE4; STAT3; ID4; EPAS1; HHEX; SOX9; SOX2
Down-regulation	162	FHL2; HOXA5; GMNN; HOXA10; NFIL3; FOXJ3; TLE1; CCNA2; ABL1; USP22; SUZ12; XBP1; NUP62; BHLHE40; APEX1; FOSL1; NFKBIA; PAX8; E2F6; HOXB7; MED27; ATF4; MYC; CDK7; C1D; EZH2; CENPF; FOXO3; RCOR1; WHSC1; SP2; ECD; SOX4; SERTAD2; NRIP1; RNF4; MSX1; AGO2; SUV39H1; RUNX3; ID2; HOXA11; BRD8; CTCF; ELF4; ZNF195; EYA2; MED6; ATF7IP; SIX1; ADNP; HMGXB4; TCF3; NFYC; RNF111; MGA; FOXM1; EN2; UBE3A; CBX3; TFDP2; COPS5; ELF3; ZNF268; ZBED1; OVOL2; KAT7; ARNTL2; THAP1; BCOR; HTATIP2; ZZZ3; RBBP7; SFPQ; E2F3; RBBP4; AATF; FOSL2; EWSR1; ZNF654; CEBPA; RLF; GATA6; DDIT3; TAF1D; SMAD7; TSC22D1; TCF7; ZNF146; SOX17; REPIN1; ZFHX3; HOXA7; JARID2; SMAD6; ING3; ZNF32; PRDM4; EP300; UTF1; MAFG; BACH1; BNC2; ZBED4; BATF3; STAT1; FOXF1; MAFF; BCL3; EDF1; BRD3; TRIP4; SP140L; HMG20A; ZNF22; HIC2; E2F8; PUF60; TBL1XR1; AFF1; E2F2; HOXB13; ARNTL; ZFX; TERF1; BHLHE41; REL; TGFB1I1; MAZ; MYCN; RUNX1; TEAD4; VEZF1; PITX1; IRF1; PLAG1; JUND; RERE; ZNF593; ZBTB18; MDM4; CREB3L1; MAGED1; HOXD1; AR; CTBP2; HOXB6; BCL11B; FLNA; TFEC; NKX3-1; POU4F1; IKZF1; ZNF160; TOX; ATF3; MYB; LMCD1; HOXC10; PIR; NFATC4; JUP