Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID32210	Sotrastaurin	GSE70138	HA1E	Human	24h	10uM	EID0145

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	TSC22D3; CREM; SSBP2; ETS2; BRD7; GTF2IRD1; NR3C1; TCFL5; MXD1; CBFA2T2; HSBP1; STAT4; FOXE1; ZBED2; TBP; SMARCA5; RBL2; NFIC; TSC22D1; SKI; NFIX; GFI1; CITED1; SAP30; URI1; BTG1; ZBED1; TERF2; STAT5A; ORC2; KDM5D; KAT5; DPF2; SUMO1; MLX; CUX2; TFCP2L1; PRDM1; HOXB2; ZNF14; ZNF165; PHF8; LHX2; EBF2; PAX9; NR1H2; RBPJ; ZNF573; PROX1; SOX21; NR3C2; TFDP2; KDM5B; ASCL1; NFKB1; ZNF586; MYCN; HOXB5; TFE3; NSD1; CCNE1; TLE2; POU2F2; NR2F6; ATF7IP; MEOX1; ADNP; NPAT; SATB1; TFAP2C; HNRNPD; ZNF671; WHSC1L1; MAFB; ZNF528; RFX7; PITX1; RARA; NAB1; MGA; AIP; SMARCE1; PIAS3; IRX5; CD3D; TRRAP; IFNB1; TGIF2; TBX2; ATF3; RNF141; AFF1; KLF4; STAT2; HTATIP2; ELK3; HOXB6; NEUROD1; BRCA1; BHLHE40; PBX3; ISL1; POU2AF1; GRHL2; HDAC11; ZNF205; ZFY; TBL1X; FOXF1; KLF3; DDX17; TCF12; EPAS1; FOXA1; HOXC10; ING2; PFDN5; BCL11B; MBD2; PHOX2B; FOXI1; PRDM2; BRD4; EGR3; BARX1; TXNIP; GLI3; FOXO3; PHF20; LZTS1; MKL2; MAF; RBPMS; SMARCA1; ARID5B; PCGF2; CEBPG; ID1; FOXO1; RUNX3; FOSB; PPARGC1A; SIAH2; SSX1; SMAD1; ZBTB16; EHF; HEY1; NFIB; MYB; FOXC1
Down-regulation	137	LOXL2; DDX5; SAFB2; YEATS4; YEATS2; GATA6; WT1; ZNF580; ZNF512B; RLF; MTA1; ZNF184; LMCD1; RCOR1; ZBED4; MEF2A; CRYM; CCNC; SIRT7; RNF6; WWTR1; HOXA7; CSDC2; ATF5; TEAD4; ELF4; IKBKAP; MYRF; HDAC3; BHLHE41; MED13; FOS; CBX3; CAPN15; LEF1; HOXA10; HIPK1; CALR; HOXA5; KAT6B; IFI16; EMX2; ZMIZ1; SP140L; MTF2; ZFPM2; ILF2; ARID4B; BATF3; CREB3L1; ZNF177; ACTL6A; GCFC2; BTAF1; KLF1; MED15; NPM1; GTF3A; BCL3; HOXD1; RNF138; BCLAF1; MED1; CHD9; USP16; APEX1; CNOT2; SALL1; JUNB; MEIS2; MNDA; UBE3A; CHD1; TLE4; ZNF189; PQBP1; CEBPZ; BPTF; C1QBP; ATF4; TLE1; FOXJ3; BRD8; ZNF44; ZNF562; TRIB3; ENO1; ZFP36L1; TRIM29; CSDE1; PTTG1; PDLIM1; E2F8; TDP2; HMGN3; SMARCB1; ZNF217; SMAD6; BCL6; SMAD3; SUB1; TAF10; TBL1XR1; SFPQ; ID3; PAXBP1; ZEB2; ID2; SMAD7; TGFB1I1; HOXC6; ZNF195; ZNF266; TGFB1; ZEB1; HMGB1; ERG; HIRA; WWC1; JUP; NR2C1; IRF1; ZMYM2; RRN3; HOXA11; ZNF107; ZBTB38; SPEN; HIVEP1; MSX1; FLNA; CREG1; IRF9; DMTF1; OSR2; MYBL1; SOX9