Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID31348 Tie2-kinase-inhibitor GSE70138 SKL Human 24h 10uM EID0135
Types Number Response transcription factors
Up-regulation 32 TCFL5; ZNF586; ZNF587; HOXA10; CTNNB1; RBBP4; NR2C1; ZNF134; HDAC4; ZNF551; TRIM28; BBX; REPIN1; ZNF211; SAP18; PIAS2; ZMYM2; MSX1; MTA1; BRD2; SATB2; BCL3; EYA2; TSC22D1; TLE1; BTG1; TRIP6; MAGED1; MAF; NKX3-1; TXNIP; MAFB
Down-regulation 57 ESRRG; FHL2; BHLHE40; NR4A2; TULP3; HOXB2; EPAS1; PAX5; ZSCAN31; MEIS2; NR4A3; NR4A1; ATF3; TCF4; PITX2; MEIS1; EGR2; MEOX1; SIX3; TLE4; CREB3L2; PAWR; ZFPM2; TRIM29; POU2AF1; NR3C2; TCEA1; NR2F1; FOXN3; GRHL2; HIC2; TCF21; SOHLH2; TFEC; HMGB2; ELF5; PSIP1; ERG; CTBP2; MYBL1; ERBB4; EHF; STAT4; TWIST1; PBX1; WT1; ETS2; ARNT2; DACH1; HOXB6; ZNF165; MECOM; TOX3; GATA6; ECD; NFATC3; IKZF1