Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31273	Alectinib	GSE70138	SKL	Human	24h	1.11uM	EID0135

Response Information :

Types	Number	Response transcription factors
Up-regulation	69	TBX2; ZNF589; SMARCC2; SSBP3; HOXA10; MED12; MXI1; CBX4; CALCOCO1; YWHAB; ZNF75D; TGFB1; IRF2; HOXA11; ING4; NKX2-1; NLK; HDAC5; SNAI2; NAB2; KDM5C; CERS4; RXRA; BACH1; MED15; CHD3; HIPK2; SOX13; KLF13; UBE2B; ATN1; SP2; CALR; SSX1; ZNF281; KLF11; TWIST1; TP63; FOXC1; ELF4; MAFB; NR4A2; SPIB; NFE2L3; NFATC3; EGR2; IRF4; LITAF; CREB3L2; POU2AF1; BTG1; MEF2C; CITED2; DAXX; SOX11; HOXB2; NR2F1; LEF1; TSC22D1; EGR3; ESR1; RBPMS; VDR; HMGB2; PBX3; MYRF; IRF6; PEG3; HOXC6
Down-regulation	59	PARP1; NFE2L2; CNOT2; ZNF146; SHOX2; SFPQ; ZNF302; TRIM27; WWTR1; ZNF93; PMS1; NFIB; MED21; RBM39; DNAJC1; RBBP4; HSBP1; NFATC1; ZBTB38; PURA; ZNF562; ZSCAN18; CSDE1; ZNF189; ZNF91; TEAD1; WWC1; HIPK1; TRRAP; RLF; SAP18; JUND; CTNNB1; LOXL2; CRY1; SPEN; GATA6; ELF5; ZEB1; TCF7; INSM1; BAZ2B; KLF2; HLTF; E2F3; HHEX; EMX2; INSR; ZNF165; HEY1; PSIP1; BASP1; ID4; ASCL1; ZIC1; FLNA; SOX9; GATA3; IKZF1