Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31271	Alectinib	GSE70138	SKL	Human	24h	10uM	EID0135

Response Information :

Types	Number	Response transcription factors
Up-regulation	73	TCFL5; SIRT7; DAXX; TERF2; RBBP7; SP140L; YBX2; ZSCAN32; ING2; HMG20A; TRIM27; NR3C1; ZNF7; JAK2; MAX; ZNF200; MEOX2; SND1; CAMTA2; TAF12; ZNF410; NR1H2; HMGA1; RNF141; KLF7; PIAS4; RNF14; ARNTL2; SIAH2; ZNF516; ZHX2; PGR; ADRB2; POU4F1; CUX1; ETV5; OSR2; SOX10; RUVBL2; NAB1; SIX2; HLX; PBXIP1; TP63; THAP7; PSMC3; ATF7IP; TLE4; TCF4; SATB2; ZNF532; MYB; UBE2I; IFI16; ZNF423; RBPJ; TGIF1; STAT4; EYA2; NFATC3; IRF1; MYCN; ZNF652; EGR3; SMAD1; BTG1; VDR; EGR2; EHF; MEIS1; HOXB7; KDM5D; ATF5
Down-regulation	116	USP22; WWC1; NR1D2; NONO; SFPQ; CTBP1; ZMYND11; DDX17; LHX2; HNRNPD; TAF9B; TGFB1; NPM1; RUNX3; SF1; FUBP1; ERBB2; HOXC13; NEUROD2; SHOX2; BTF3; NCOR2; MAGED1; SOX9; SOX2; ZNF529; ZNF302; CNOT2; DDX5; PBX1; CCNC; CBFB; NR2E1; TSC22D2; BPTF; ZNF160; SMARCC2; ZBTB38; JUND; CHD1; MYT1; AES; TRIM29; MYEF2; ST18; HEY1; ZNF43; MAK; TCF20; CAMTA1; MYT1L; ZSCAN31; VGLL4; DEAF1; IKZF3; ING3; FOXM1; BCOR; ZIC1; NHLH2; RUNX1; BRD8; NR4A3; PBX3; EPAS1; ZNF331; ZNF667; TEAD4; ZFP36L1; NRIP1; AHR; CDK2; LMCD1; RAN; PRRX1; BAZ2A; ZNF91; ZNF536; BAZ2B; PNRC1; NR4A2; TCF7; ZNF721; TRPS1; ERG; EN1; NKX2-2; HOXB13; E2F3; DEK; ZNF83; FOXA1; MED13; MYRF; ZFPM2; ELF1; PAX6; HMGN3; JUP; LEF1; TCF7L1; ELF3; CRY1; DLX2; MAFB; SMAD7; INSR; TSC22D1; ID4; CREB3L1; TOX3; BASP1; FLNA; ID1; IKZF1; E2F2