Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31247	Vx-745	GSE70138	SKL	Human	24h	10uM	EID0135

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	GATA2; CHD4; WHSC1; TFDP2; SOX17; ESR1; ERCC2; YY1; HOXD11; HOXD3; ZNF84; BATF3; KLF10; DEAF1; TCF12; ELF4; DAXX; ELF3; HDAC1; PHOX2B; SP4; MEOX1; ZNF606; ZKSCAN8; HOXD10; SSBP3; CHD3; HOXD1; HDAC9; EYA1; WT1; NKX2-1; OSR2; RFX7; SOX5; AHR; BHLHE41; PRDM1; ARID3B; GFI1; ZNF304; YEATS2; PSMC3; ZBED4; FOXJ1; MEIS1; RERE; HOXA11; RCOR1; ZNF211; HIVEP2; NHLH2; SKI; MSX1; HIPK3; RNF138; ZMYND8; YEATS4; RARA; CRYM; MECOM; TOX; ZFHX3; BCOR; RBPJ; SAP18; SMAD6; TGFB1; BRD2; RAD21; SIX1; NR0B1; NFE2; IRX5; SIX3; ZMYM2; SOHLH2; STAT5A; RBL2; PBXIP1; CUX1; MYRF; ID1; EPAS1; CUX2; KDM5D; ZNF22; OVOL2; HMGB1; NFATC3; NCOR2; ZNF423; TAF10; NCOA2; HMGB3; NR4A2; PCGF2; TEAD4; EMX2; HIC2; ELK3; ERBB4; EGR3; STAT4; HOXB2; BMI1; TAL1; HOXB6; SSX1; MYCN; MYB; DACH1; ZNF217; KLF6; MYBL1; ATF3; EGR2; TXNIP; ID4
Down-regulation	104	THAP11; COPS2; TRIM29; CAPN15; BLZF1; UBE2I; CCNC; PITX1; NKX3-2; ZNF692; SOX2; BBX; MAFB; SMAD3; TAF9; NR2F1; DDX17; ZNF302; ING3; MKL1; RBBP5; NOC2L; TBX3; FOXF1; HES1; NEDD8; LIN28A; TCF4; CTNNB1; USP16; NRBF2; MAF; ZNF573; LHX1; PNRC1; HBP1; KLF2; TRIB3; TSC22D2; CDIP1; ZNF85; TCEA1; SMARCD3; ZNF91; RBM39; TOX3; BIRC2; HLF; SOX15; ELF5; HSBP1; BTG1; FOXF2; SOX10; ZNF146; REPIN1; SPIB; DDIT3; BCL6; TCERG1; TCEB2; NRIP1; DNMT3B; ADNP; LEF1; SOX9; ARID4A; TP63; NFYC; TOB1; TLE4; FOXD1; KAT6B; TCF7L2; ZNF160; REL; NFAT5; ZEB2; CITED2; CARHSP1; SPEN; DMTF1; RREB1; TGIF1; BAZ1A; PAX5; POU4F1; MNAT1; IRF8; MNDA; ATF5; NANOG; ZNF721; PLAGL1; ISL1; MXI1; MEF2C; DLX2; SMAD1; RELB; ECD; NR3C1; IKZF1; E2F2