Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31152	Saracatinib	GSE70138	SKL	Human	24h	10uM	EID0135

Response Information :

Types	Number	Response transcription factors
Up-regulation	165	TDRD3; HMGXB3; HOXC5; MYBL1; TGFB1; PHOX2B; FOS; NKX2-1; EGR4; ZNF816; EHMT2; TAF1; ERBB4; PHF1; ZNF205; EGR2; THRB; HAND2; ZNF556; RING1; CREB1; ZNF467; HIPK2; ZNF444; GATA2; HNF4A; SRCAP; ZNF835; MYCBP; GRHL2; PDX1; HOXB3; TAF6; TCF15; HMX1; FOXM1; CIITA; ZNF692; PQBP1; CIC; RERE; MKL1; PSMC3IP; SPI1; MITF; MAML3; ZSCAN2; ZNF224; SND1; MLLT10; CALR; TTF2; SP1; MYRF; EGR1; TFDP1; HOXD11; WWC1; L3MBTL1; SAP18; CSDE1; HLX; BRCA1; BCL6; EPAS1; STAT2; ZNF274; PRKDC; SPDEF; ERF; CTNNB1; NFIX; TWIST1; ESR1; TCF21; ZNF551; SMAD6; NFE2L3; LIN28A; AEBP1; HOXC4; PITX1; SPIB; SREBF2; HLF; CAMTA2; WT1; LMCD1; NEDD8; ZNF219; RCOR1; ZNF134; OVOL1; CNBP; SUPT3H; SOX3; ZMIZ2; EZH2; PSMC3; HAND1; SLC2A4RG; ELF4; PDLIM1; ZNF117; ZNF350; HMGA1; ZNF606; RBFOX2; HOXB5; FLI1; ZNF264; ZNF180; NR1H2; HIPK1; TRIM33; TCEA1; SOX17; NR1I2; NONO; BCL11B; ZNF532; GATA3; MTA1; HOXB6; TFCP2L1; GFI1; CARHSP1; CBX7; FLNA; ZNF544; ID1; NR1H3; AR; TFAP2A; IRF6; FOXL2; FOXA1; MEIS2; CRYM; OVOL2; NR4A1; HMGN3; BHLHE41; PAX5; NFATC3; EGR3; CUX2; NKX2-2; ZEB2; MNDA; TFEC; ID3; ZFPM2; DAXX; IRF4; MYCL; ZBED2; ZFP36L1; PEG3; ZNF91; MAFB; ST18; ZNF423; TXNIP; MEIS1
Down-regulation	178	FHL2; MNT; CDK7; XBP1; ZNF302; NFIL3; NUP62; HIF1A; HDAC2; SMAD3; SOX4; TCF12; FOXO3; ZNF189; NPAT; MYC; RFC1; NFE2L2; CEBPG; ZEB1; ABL1; YWHAB; HNRNPD; SMARCA5; ZFP64; FOSL1; SERTAD2; TBP; PRDM4; TAF9; SMAD1; BACH1; CNOT1; ZBTB11; TLE1; PHF20; KAT6A; NRIP1; HES1; CHD9; CNOT2; RYBP; RNF111; NR2C1; RBBP4; TRIM32; HMBOX1; DPF2; CHD1; USP22; TGIF1; RAN; ATF6; MEN1; DDX5; MED7; CTR9; EED; MED6; HMG20A; BRD3; TCF4; ZMYND8; TBPL1; MLX; DNAJC1; VEZF1; CRK; ZNF146; NCOA6; PLAGL2; MED27; PATZ1; RB1; HOXA5; RBM14; FOXJ3; DDIT3; BLM; ZNF281; HOXA10; POU2AF1; ADNP; CEBPD; STAT3; ARNTL; HOXC10; SNW1; CREB5; KDM2A; RNF14; BRD8; BTG1; TRIM29; SCAND1; BCLAF1; HCFC2; TBL1XR1; ZNF160; MAFG; KLF10; ECD; BCL10; CCDC59; WWP1; HMGXB4; HSBP1; WWTR1; TRIP4; BHLHE40; APEX1; INSR; SPEN; PHIP; CBX3; SFPQ; RBPJ; ZNF148; UBE2I; PIR; NR2F6; UBE2B; MDM2; CDK8; TP53; SOX13; NCOA4; HTATIP2; CRY1; NLK; STAT5A; DNMT3B; TOPORS; SP100; RORA; MED21; HMGB2; PNRC1; TCF7L2; KLF9; HBP1; ZNF12; ZBTB16; ZBTB38; RUNX1; ILF2; ZMIZ1; PUF60; CEBPZ; CDC5L; MED23; MNAT1; TLE4; SIX1; SATB2; FOXC1; ZNF22; AFF1; YBX3; CTBP2; BMI1; TRIM22; FOSL2; EYA2; NFIB; TP63; BCL11A; MYB; KLF6; TFAP2C; TRIP6; ELK3; ZBTB18; TDP2; CREG1; STAT1; SOX9; ATF5