Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31145	Mitoxantrone	GSE70138	SKL	Human	24h	10uM	EID0135

Response Information :

Types	Number	Response transcription factors
Up-regulation	183	FOXM1; HMGA1; NFKB2; TCF21; CENPF; INSM1; SSBP3; HIPK2; ESRRG; NR6A1; NFIX; SPDEF; NFKBIB; PHOX2B; NHLH1; TGFB1; IRF6; MED25; CCNA2; DRAP1; THRB; ZIM2; GATA1; NKX3-2; PTTG1; NKX2-1; GRHL2; HOXC11; FOXJ2; BCL11A; ZNF816; LHX3; CDK9; PLAGL1; NEUROD1; ZNF580; WDR77; NR1H2; PSMC3; CCNT1; ZNF528; HOXB5; RARG; KLF1; KDM5C; HAND1; PROX1; NOC2L; HOXC5; PPP1R13L; NFAT5; TFCP2L1; FOXF2; PAX9; PITX1; PDLIM1; BNC1; RORC; ASH1L; TFDP2; ZNF215; NR0B2; CNOT3; MEIS1; SREBF2; CIITA; ACTL6B; CDX2; PRDM14; NR1I2; TCF20; TEF; VENTX; FUBP1; MBD2; TRIM28; CDX1; ZNF536; OVOL2; ZNF835; MNX1; TAL1; TFAP2A; PRDM1; HLF; CTNNB1; FOXE1; JUP; GFI1B; KDM5A; PHF1; PHIP; TTF2; TWIST1; NR1H4; DLX2; ADRB2; IRX4; TOX3; PEG3; C1QBP; WNT4; JUNB; VGLL1; FOXL2; TRIM24; ZIC3; KDM4C; EGR4; MYBL2; FOXF1; FOXA2; SOX15; MXD1; RUVBL2; FOXJ1; EHF; ZNF432; HNF4G; HIVEP1; MYCN; CALR; POU2AF1; TBX1; PNRC1; ZNF345; EPAS1; DNAJC2; HIRA; ID2; FEZF2; ST18; PAX6; ZNF589; JAK2; ATOH1; HSF1; CRYM; TOPORS; NKX2-2; MYB; RFX5; SIX3; ZNF544; HDGF; EN1; ASCL1; WWC1; KLF4; BHLHE41; MYCL; HTATIP2; LIN28A; JUND; MYBL1; KLF11; PSIP1; BCL11B; CDK2; GMNN; SOHLH2; ETS2; TFEC; HDAC9; TLE4; TP63; CBFA2T3; IRF4; DLX5; SPIB; IRF1; RUNX3; ARNT2; MECOM; RBPMS; ZNF423; ZNF331; ID3; ZBED2; TXNIP; TRPS1; FLNA; ID1
Down-regulation	174	THAP11; MYC; CDK7; SOX4; TCF12; NRBF2; TSC22D3; ZNF131; SMAD3; MNT; ZNF267; VEZF1; HOXA10; ERBB2; CHD9; HES1; RLF; RNF4; BRD3; FOXO1; HMG20A; CREB1; SIX1; ZNF189; MAGED1; NFKBIA; FOXJ3; ZNF7; ZNF12; BHLHE40; IKBKAP; SMARCC2; NFE2L1; CLOCK; NR2C1; PURA; NCOA4; TAF9; BCL10; RBBP4; CRK; PATZ1; IRF2; IFI16; ZZZ3; ZBTB1; ZHX2; ZFP64; TBP; RCOR1; ZNF22; APEX1; BRD8; HNRNPD; ZNF410; TAF7; DPF2; ZNF443; SMARCD3; CTCF; HOXA11; ING2; ZNF281; ZBTB11; ZNF430; NR2F2; ZMYM2; TLE1; ATF1; CBFB; ZKSCAN7; HDAC4; SATB1; ZNF32; PSPC1; FOXO4; USP22; ARID4B; RBBP8; RERE; ZKSCAN1; ZNF24; HSBP1; ADNP; TRIM32; JARID2; NFIL3; RNF111; RARA; YWHAB; ZNF84; CHD7; SMAD4; VGLL4; MED13; ZNF652; HMGN3; RNF14; ASH2L; DDX5; SMAD2; PIAS3; NAB1; STAT6; GABPB1; MEF2A; UBE3A; TSC22D4; NCOA1; PBRM1; SPEN; MGA; MSX1; MED6; HDAC1; SERTAD2; TGIF1; KAT7; PCGF2; HOXC10; KLF10; REST; NR0B1; NRIP1; HMGA2; HMBOX1; SP140L; IRX5; TRIM22; TBL1XR1; MAFG; MEOX1; CRY1; RBPJ; GFI1; TSC22D1; SP3; RYBP; DDIT3; RUNX1; ZNF711; MNAT1; SMARCE1; ZNF532; MEF2C; ZBTB18; BAZ2B; ZNF232; HEY1; BCL3; HOXC6; CITED1; SUB1; ZNF91; BMI1; NCOR2; ZFP36L1; EGR3; SMAD1; FOXC1; MED1; ZNF217; TBL1X; ECD; LMCD1; LEF1; ELK3; MTF2; HOXB7; MAFB; SOX9; RELB; NR3C1; NFATC3