Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31042	Alectinib	GSE70138	SKL	Human	24h	10uM	EID0134

Response Information :

Types	Number	Response transcription factors
Up-regulation	82	MTF2; CALR; ARRB1; SSX1; GTF2IRD1; MED1; ZNF23; ZBTB20; AFF1; TCF20; WDR77; HBP1; SIM2; CREB1; CDK9; TERF1; RBBP5; DBP; TGFB1; CUX2; SOX11; ARID4A; ING3; NR3C2; EGR3; SND1; JARID2; MED24; HNRNPD; HMG20A; MAGED1; ZSCAN31; DACH1; ZKSCAN1; WNT4; JUNB; SATB2; CENPB; SMARCE1; NFATC1; TCF7; SMAD2; ZNF587; FOXF1; HMGB3; ID3; LEF1; WWP1; FOXE1; HLF; PCGF2; KLF9; TBX3; NFATC3; ZFP36L1; TCF4; CERS6; SP3; HLTF; PRKDC; ZNF423; SMARCA1; TDP2; ZNF331; TSC22D1; PITX1; KLF13; ZNF217; CITED2; CHD7; MYB; AEBP1; LPIN2; ETS2; HOXC6; MECOM; MAF; RBPMS; ID1; ASCL1; HOXC10; NR4A2
Down-regulation	55	UBE2I; MAFF; DDIT3; HOXB2; ARL2BP; PFDN5; AGO2; MED21; C1D; POU3F2; YBX3; JAK2; NR1H3; CCNE1; TRIM29; PBX1; HOXB6; LMCD1; ZNF239; ATF5; TFEC; MBD2; ATF4; SOX2; ESR1; GATA6; FOXG1; ZBTB16; SMARCA2; ZSCAN18; TFEB; SP140L; THAP10; ID4; TP63; CRY1; CRYM; HOXB7; ELF5; KLF6; PBX3; IRF6; MEIS2; ZBED2; BMI1; MEIS1; MAFB; FOXO1; MYBL1; FOXC1; EHF; PSIP1; EGR2; BHLHE41; WT1