Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31019	Vx-745	GSE70138	SKL	Human	24h	3.33uM	EID0134

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	CEBPZ; SIRT7; CITED2; SUV39H1; TBX21; PHIP; HOXA4; TGIF1; NR1D2; KAT7; KMT2A; BCLAF1; HOXA7; HOXC10; SOHLH2; SP140L; NR2F2; PQBP1; PRMT2; SSX1; TOB1; CDK9; CBX7; REPIN1; ZNF394; JARID2; AFF1; CHD1; STAT4; RNF141; CD3D; SIX1; CTBP2; ELF4; HBP1; SIX2; HOXC4; ING3; PSMC3IP; RREB1; RBBP7; ZBTB1; HTATIP2; IRF1; RUNX3; CALR; JUNB; RARA; PTRF; HIVEP2; FLNA; TCF7; NFATC3; TRIP6; HOXB7; CENPF; SMARCA2; MYT1L; PIR; ERBB4; HIC2; TBL1XR1; NEUROD1; MXI1; NR4A2; TP63; GATA6; ZIC1; AHR; OSR2; FOSL2; NKX2-2; FOXC1; PAX6; KDM5D; BHLHE41; HOXC6
Down-regulation	83	E2F6; CEBPB; E2F5; TLE4; SOX11; ZNF83; ZNF354A; PLAGL2; HEY1; BCL6; FOXO1; VGLL4; NFKBIB; TCF12; MSX1; HHEX; BACH2; IRF8; HMBOX1; UBE2I; ZNF232; PITX1; RYBP; RBPJ; ZNF410; SMAD1; L3MBTL1; ELK3; TADA3; YBX3; REL; MBD2; TGFB1I1; PROX1; TCF4; ZNF141; ETS1; KLF5; EGR2; TWIST1; ZNF43; MYB; DLX2; ZSCAN31; CEBPD; BASP1; IRF4; LMCD1; SOX9; RUNX1; PBX1; TOX3; SMAD3; ZEB1; ATF3; NFE2L1; CBFB; ID4; ZNF532; DACH1; ZFPM2; ESR1; NFAT5; DLX5; NRBF2; IRF7; ID1; ID3; HMGA1; ZNF281; ST18; MAF; TAL1; ZFP36L2; TRIM22; POU2AF1; PAX5; MNDA; ZFP36L1; LEF1; IFI16; ZBED2; BCL11A