Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID31014	Dabrafenib	GSE70138	SKL	Human	24h	1.11uM	EID0134

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	NR1H3; SSX1; PPP1R13L; MTF2; SUV39H1; ZBTB14; ERG; DACH1; IRF6; FLI1; LHX6; NR3C1; PQBP1; HOXC11; MYB; NFATC1; NFE2L3; SNAI1; IRF2; STAT5A; ANKRD1; OVOL1; HOXA7; TFE3; MED12; DDX54; PITX2; HSBP1; TFEC; NFX1; TBX3; BTG1; LIMD1; KDM4A; KMT2A; MED14; BLM; NFE2; CHD9; PROX1; CDX1; ZNF443; ZNF580; PMF1; MED13; KLF1; ZBED1; POU4F2; FOXL2; BCLAF1; BHLHE41; TCF12; VGLL1; POU4F1; HDAC5; SOX10; SIX3; ETV4; PSPC1; ARNTL; GATA2; TAF5; SAP30; PBXIP1; HNF4G; MAFF; ZNF22; EN1; ZNF107; MLLT10; MED17; ZMIZ1; TDRD3; TERF2; ZNF165; TRIM29; IL16; MYCL; ESR1; LYL1; JAK2; ELF5; CCNT1; SP100; PAWR; TP63; CREM; FOSB; CREB3L2; TCF4; TRIM32; CD3D; OLIG2; GATAD2A; SOX15; ZNF430; IRF9; BCL11A; NPAT; ID4; ZBED2; NKX3-1; ELK3; PHIP; GATA6; HIVEP2; ATN1; KLF6; ZNF721; CBFA2T3; JUP; IFI16; HDAC9; ZIC1; CRYM; KDM5D; TRIM22; IRX5; BASP1; STAT1; PAX5; POU2AF1; TXNIP; ZHX2; NFIB; HOXC10; ASCL1; FOXC1; HOXC6; NFATC3
Down-regulation	128	PRKDC; COPS5; ZNF224; TRRAP; TCEA1; SALL1; CTBP1; ARNT; ZKSCAN5; ZFP36L1; ABL1; LZTS1; HIVEP1; TEAD3; ZNF7; CTNNB1; HOXB13; CSDE1; LOXL2; TAF11; SUMO1; NR2C1; ZNF354A; KLF7; SLC2A4RG; DNAJC2; SHOX2; MNT; MECOM; TAF9B; PEX14; ZFX; SRF; CAPN15; NFKB2; HNRNPD; EP300; BNC2; PBX2; PITX1; TLE2; RING1; HDAC4; ASH2L; CDK8; CENPB; ZNF329; XRCC6; HOXB6; RRN3; CHD3; DDIT3; PBRM1; CUX1; EWSR1; ZNF217; STAT6; EHMT2; RUVBL2; TOX; MED7; HOXB5; CBX6; TADA3; ZNF652; ZNF500; ZFHX4; NOC2L; TDP2; RREB1; BRD4; FLNA; NFIC; ZNF512B; NCOR2; ZNF573; ZNF281; ZNF623; PLAGL2; FOXD1; PTRF; FOXN3; PEG3; AHR; CITED1; ZNF264; TOB1; ATF5; CREB3L1; ZNF211; DDX17; COPS2; UBP1; SMARCD3; FOXF1; TBL1X; ISL1; SOX11; TRIB3; ZFPM2; MDM2; RBL2; MEIS1; WT1; NCOA2; TLE4; ZNF302; MYBL2; NFE2L1; ID1; MYRF; LEF1; KLF13; AFF1; SMAD6; CRY1; PBX3; CITED2; NR2F1; KLF11; NR4A1; MYBL1; EMX2; MEIS2; MAF; HEY1; GLI2; PSIP1