Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID30888 Tie2-kinase-inhibitor GSE70138 SKL Human 24h 1.11uM EID0133
Types Number Response transcription factors
Up-regulation 57 PPARG; TRIM32; RNF14; MED7; ZNF189; THAP1; MED1; GATAD2A; TULP4; RBM14; EDF1; ZBTB38; PHF2; CREM; ZNF267; ELF1; MYT1L; CRY1; BNC2; ZNF329; HSF2; TCF7; MED13; FOXO1; KAT7; ZBTB18; HES1; RNF4; SMAD2; ZNF226; ING3; CHD1; PIR; PITX2; ATF7IP; SUB1; TSC22D2; CRYM; INSR; MAGED1; HTATIP2; HOXB6; SIAH2; ASCL1; HOXB7; KLF2; TOX3; FOXD1; KLF10; TXNIP; LEF1; MSX1; ZBTB20; ZNF423; POU2AF1; BASP1; HOXC6
Down-regulation 74 CREG1; NRIP1; EHMT2; PITX1; TCEA1; BTF3; SPIB; SUMO1; CBFA2T2; ZNF512B; ATF3; PFDN5; OVOL2; ZNF394; CALR; MYBL2; TEAD4; NPM1; HMBOX1; ZNF232; TRIM24; TRIB3; MEIS1; RBBP8; HOXB13; GTF3A; ATF5; EYA2; ZNF133; CENPF; ZNF467; PBX1; CNBP; HDAC9; RNF138; ID1; ZNF195; GMNN; YBX1; WWC1; MAF; CBFA2T3; KLF4; YBX3; TULP3; ISL1; FOXK2; SOX11; GLI2; TFAP2A; SMAD1; ZFP36L2; DAXX; TFAP2C; ARNT2; EHF; MEIS2; DMTF1; PEG3; BCL11A; MYB; ZBED2; NFE2; TCF4; PBX3; MYCL; FOXG1; TRPS1; JUP; TRIM29; ID3; IRF6; SOX9; NFATC3