Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID30813	Alectinib	GSE70138	SKL	Human	24h	1.11uM	EID0133

Response Information :

Types	Number	Response transcription factors
Up-regulation	75	TCFL5; KAT6A; SPEN; KDM5A; UBE3A; KAT6B; DNMT3B; WDHD1; TCF7; POLR2A; YEATS4; TMF1; ATF2; MED7; CTNNB1; HMG20A; RRN3; MYRF; TCEB2; ZEB2; TTF1; BLZF1; RFX7; JARID2; ZBTB24; RBBP4; SUB1; TULP4; TAF1A; LDB1; RYBP; PIR; SETD3; PHIP; HOXA7; RBPMS; NFAT5; KLF7; FOXL2; AEBP1; RNF141; KAT7; BLM; MED6; HSF2; BRIP1; ZNF532; PITX2; PIAS1; GATA4; SMAD5; ERBB4; ETS2; NANOG; FOXJ3; MEF2C; BBX; ATF3; AFF1; SFPQ; WHSC1; TAF10; ZKSCAN1; TAF9B; WT1; HHEX; ZNF423; KLF10; CITED2; HOXC6; RUNX3; PEG3; NR1D2; MECOM; ASCL1
Down-regulation	76	ZNF83; MAF; GTF3A; TRPS1; SMARCC2; CDK2; ELF5; KAT2B; MBD2; HMGB2; HDAC1; BTF3; DLX5; POU2AF1; CBFA2T2; THAP11; FOXG1; BACH2; UBE2B; GTF2IRD1; SP100; NCOA1; ZHX2; ZFP36L1; E2F5; CBX6; ZFHX3; WWTR1; SMARCA2; TBL1X; TAL1; TDP2; SOHLH2; TRIM29; NPAS2; CREM; PAX6; ZIC1; TGFB1; RBPJ; CCNE1; ELK3; MYBL1; SMAD1; ELF4; ZBTB38; ZBED2; NCOA2; FOSL2; MEOX1; ELF3; ZBTB16; HEY1; TLE1; EYA1; GMNN; DLX2; TXNIP; SOX9; TOB1; STAT4; NFIB; SATB2; TRIP6; POU4F1; ZBTB20; NFE2L3; DAXX; KLF4; ESR1; EMX2; PBX1; TFAP2A; TOX; DACH1; NFATC3