Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID30811	Alectinib	GSE70138	SKL	Human	24h	10uM	EID0133

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	TOPORS; FOXJ1; NR3C1; BLM; TRIM24; ERG; TFAM; CHD4; YEATS4; KDM5B; MTF2; CCNT1; BCOR; ZBTB20; ELF3; NKX2-1; KMT2A; TCF7; SMARCA1; CRYM; MYF6; CBX5; CLOCK; GATA2; ZNF148; HMGB1; ING2; HDGF; CBX3; BCLAF1; TRIP4; TMF1; RAD21; KLF10; NR0B2; AEBP1; ZNF331; NFIB; CIR1; MED1; MAZ; ZNF711; KLF7; CALR; KDM5D; JUND; TCF20; TRPS1; ZNF329; CRY1; MYT1L; ZSCAN16; HOXA7; DNMT3B; CREB3L2; PBX3; CD3D; MAK; MEOX2; NFAT5; CREM; ING3; SSBP2; UBE2B; ERBB4; NFE2; ZNF721; ACTL6B; TEAD1; NAB2; ZNF22; ID1; HMGN3; TAL1; ZNF83; KLF6; ZNF217; BRD2; ZFPM2; ZNF160; ZBTB43; MEF2A; TBL1X; LYL1; SPIB; ESRRG; ZNF24; HMGB3; HIVEP2; KLF9; SIM2; BTG1; JUP; ZSCAN31; NR1D2; RBPJ; GFI1B; ZBTB18; MSX1; TSC22D1; ZBTB38; MXI1; TLE4; SMAD1; BCL11A; NR5A2; BCL3; TXNIP; FOXG1; NFATC3; KLF2; HOXC6; ZFP36L1; ID3; LEF1; INSM1
Down-regulation	80	CREG1; SUPT7L; BRF2; TCEA1; MYRF; DDX17; MAX; IRF1; CEBPD; SIN3B; NFYC; YEATS2; TEAD4; GTF3A; ZNF146; EHF; CENPB; DPF2; IRF2; FOSL2; ERF; PREB; SRF; CEBPB; PAXBP1; ZNF133; HDAC4; ZNF536; PRKDC; SP140; EMX2; RARA; TAF7; YAP1; STAT1; SIAH2; ZEB2; TRIM16; CREB5; GTF2F1; HOXA11; THAP11; ZNF692; TFAP2C; ZNF593; VEZF1; NFE2L3; NCOA4; BATF; PURA; MED15; SATB2; TWIST1; ZKSCAN1; KLF4; PBX1; TLE1; PCGF2; ETV5; SMAD7; BHLHE41; PLAG1; ELF5; MNDA; ZHX2; CITED1; NANOG; PITX1; ZBED2; YWHAB; MTDH; SHOX2; TRIM22; SAP30; IRF4; DMTF1; IFI16; IRF9; MAFB; SOX9