Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID30787 Vx-745 GSE70138 SKL Human 24h 10uM EID0133
Types Number Response transcription factors
Up-regulation 155 TBL1XR1; HMG20A; PLAGL2; EED; EP400; CALR; E2F2; KDM4A; ZNF665; ZNF84; SSX1; TCF20; OVOL2; PGR; ELF5; KDM5A; CNOT1; PEX2; ZNF587; TP63; ZNF10; RCOR3; ZHX3; RBBP7; TFCP2L1; EZH1; TSG101; ZNF532; BACH1; TFDP2; ORC2; ZNF672; NFX1; KAT6B; POU2F1; PRDM4; TRRAP; BLM; MED20; PRKDC; BAZ1B; TRIM32; COPS5; KDM5D; BTAF1; ATF2; YEATS2; CBX2; ZNF34; ERBB4; EVX1; ZNF510; TGS1; PMS1; HNF1B; MECP2; MED12; SMARCA2; EP300; PIAS3; PRRX1; NPAT; LHX6; NR6A1; CENPF; ARID3B; KMT2A; ZBTB44; HOXA1; CREB3L2; WDHD1; DEAF1; FOXJ1; JARID2; OVOL1; ESR1; CREB5; AEBP1; BCLAF1; HOXC10; STAT2; ZNF304; CHD7; ARID4A; OSR2; MSC; HMGB3; JUP; DLX5; TAF1D; PITX1; SPIB; ZNF586; ZNF93; ZNF195; ZNF273; TRAK1; PLAGL1; SP140L; CTR9; SRCAP; REL; VDR; ZNF667; SMARCE1; ZBTB43; NFE2; NKX2-1; DNMT3B; ZNF671; ELF3; ZNF440; FOXL2; ZNF117; ANKRD1; ZNF124; DBP; ACTL6A; FOXM1; PBXIP1; PSMC3; HOXD3; ZNF211; ZBTB20; ZNF551; ZNF107; VEZF1; JAK2; ZFPM2; MYB; SREBF1; MED14; MYBL1; TXNIP; NFAT5; FUBP1; NEUROD1; HOXC6; TCF4; HLTF; ISL1; TRIM22; MECOM; NFE2L3; ETS2; EMX2; IRF6; EYA2; ZNF331; RBPMS; NFATC3; HIRA; IFI16; CITED2; ATF3
Down-regulation 103 CRK; ERBB2; NRIP1; BASP1; HEY1; INSR; PHF1; PCGF1; PTTG1; TWIST1; CTBP1; AHR; FOXA1; HLX; TCF25; TFAM; TGFB1I1; PCGF2; RFXANK; LOXL2; PEX14; MED6; IRF1; TGIF2; CARHSP1; MYRF; CUX2; ZZZ3; CDK2; DLX2; APEX1; CREM; ING2; CEBPD; YBX3; TBX3; NKX3-2; SHOX2; ZNF266; REST; TAF11; SETD2; FOSL2; SUPT3H; HEY2; ZKSCAN1; ATF4; MAFF; TEAD4; STAT1; PBX3; NPM1; MED17; ERG; POU2AF1; CAPN15; SOX13; RLF; CDYL; MEOX1; TP53; YWHAB; MED21; BTF3; FOXN3; ZFX; RRN3; SOX18; BRD2; CREB3; CD3D; ZMYM2; RBM39; EGR2; NR2F6; CCNE1; YAP1; MTDH; PTRF; THAP11; MEF2C; AES; GTF3A; ZNF91; FOXF1; TRIB3; SMAD1; ZBED2; NPAS2; FOXD1; CITED1; ELK3; HHEX; MAFB; MED1; ID3; BHLHE41; FLNA; DAXX; TOX; IRF7; HOXB2; WWTR1