Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID30249 Saracatinib GSE70138 NPC Human 24h 3.33uM EID0125
Types Number Response transcription factors
Up-regulation 190 KDM5A; JUN; FOXJ3; TAF4B; JUP; VGLL1; TCEA2; NFIL3; NR5A2; SOX18; ZNF215; HOXD1; ELF4; MYEF2; DAXX; POU4F3; ZNF749; ERF; HESX1; ZNF345; LHX6; FEZF2; MLLT1; PRDM14; IRX4; HOXB8; TP73; POU4F2; SRY; SCAI; SOX14; NR1H4; ATF4; HIC2; DMRT1; ZNF34; CBX4; SOX3; ZNF257; EGR1; PAX4; NANOG; ENY2; ZNF675; SKIL; ZNF492; PPRC1; ZNF214; ACTL6B; LIN28A; HLX; ZNF549; NFE2L1; ZNF674; ZNF471; TULP2; POU1F1; ZNF157; EMX1; THAP9; FUBP1; KAT2A; NR4A3; FOXE1; HSF1; ZNF695; REL; TLX3; FOS; PCGF1; ZNF407; MEF2C; TEAD4; ZNF80; GCM2; ZNF81; NCOA2; SETD2; SSX7; TFAP2A; MYBL1; NEUROG2; EN1; PRDM1; PRPF6; VHL; RRN3; THRA; FOXJ2; UTF1; NR1I2; ZNF780B; POU6F2; MYT1; ZNF362; ZNF667; BAZ2A; TGFB1; LHX3; ZNF512B; TBR1; CAMTA1; ZNF682; TBX1; RYBP; HOXD3; GSC2; ZBED2; FLI1; BANP; ERG; ELF5; IKZF3; RORA; BIRC2; SAFB2; RBFOX2; CRYM; CDIP1; NFE2L2; CHD2; ZNF721; HDAC5; ZFP36L2; MAFF; SP140; SOX17; CEBPG; ARNTL; BCL11A; ZNF124; CARF; DDIT3; ZBTB3; POU2F3; BNC1; IRF6; BRDT; COPS2; PIAS1; BBX; NFE2L3; MYRF; IRF8; NPAS2; ATF3; WWC1; ZNF652; MXI1; NFATC4; SOX13; MAFG; FOXM1; CERS6; ZIC3; MAFB; KLF9; FOXN3; PRDM2; ZNF267; PPP1R13L; LITAF; ST18; DLX5; KLF11; ZNF331; HTATIP2; TP63; ARNT2; HLF; RAD21; PEG3; ZNF264; CREB3L2; NKX2-1; ZHX2; ZNF532; INSR; HHEX; CEBPB; NR1D2; NRIP1; RUNX3; HDAC9; ATF5; SHOX2; GATA6; TRIB3; LMCD1; POU2AF1
Down-regulation 91 NUP62; ATF1; HMGA2; RB1; BRCA1; MAGED1; PURA; BRD3; TBL1X; TADA3; CCNA2; UBE2I; PSMC3IP; TBP; EYA2; TRIM32; MYB; TAF10; VEZF1; SCAND1; ZBTB18; NR2F2; PIAS3; MYCBP; ZSCAN18; LEF1; TRIM27; FHL2; RNF14; SIAH2; SSRP1; MAX; RBBP4; BRD8; HMG20A; ZNF146; RBBP7; RUVBL2; GLI2; APEX1; E2F5; PCGF2; SIM2; ZNF516; CBX5; TRIP6; BASP1; BMI1; RBBP8; HLTF; ID4; ZNF274; IRF2; HSBP1; VGLL4; ITGB3BP; STAT6; XBP1; ZNF302; ZNF443; ZNF226; HOXB7; ZNF266; EYA1; NONO; NPM1; CHD9; CREB3L1; WWTR1; MEIS1; ESR1; NR2F1; CTR9; TGFB1I1; TAF7; ZMYND8; CHD7; SIX1; HEY1; HOXB6; NFE2; HMGB3; MSX1; SNAI2; ASCL1; TRIM29; ZIC1; HOXC6; HES1; ID1; ID3