Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29954	Regorafenib	GSE70138	NPC.CAS9	Human	24h	10uM	EID0129

Response Information :

Types	Number	Response transcription factors
Up-regulation	57	TSC22D3; DDIT3; CEBPG; NFIL3; ARID4B; JUN; ATF4; PSMD9; ZNF33B; PCGF1; TRIB3; KLF3; CEBPB; MAFG; KLF7; TCEA1; RRN3; SATB2; MDM2; NFE2L1; BNC2; GTF2IRD1; XBP1; TSC22D2; TCEA2; MTDH; PNRC1; RNF141; TAF10; DEAF1; ZFP36L2; KLF6; MXI1; RNF10; ZBTB38; POU4F1; ATF3; PLAGL1; FOXD1; NR3C2; KLF9; KLF2; FOXC1; TOX3; TRIM22; FOXG1; HOXB7; SMARCD3; FOXO1; KLF5; MSX1; TLE4; POU2AF1; TXNIP; NR4A2; SMAD1; PSIP1
Down-regulation	52	ETV1; CCNA2; ZNF45; DNMT1; ZNF227; E2F8; RBL1; ETV4; HES1; NR2F6; BRIP1; ENY2; MAGED1; NEUROD1; BCL3; ZNF22; NUP62; TTF1; SMAD7; PBX1; NCOA4; TEAD4; RFX5; SREBF1; MNDA; KDM5D; ERBB2; NR0B1; TFAP2C; FOXA1; TAF9B; NR2F1; RUNX1; ID2; NFE2L3; MYB; CITED1; SAP30; ELK3; ZNF232; HMGB3; WWTR1; TCF4; GATA6; PBX3; ATF5; HHEX; LMCD1; AEBP1; IFI16; ZBTB18; SUV39H1