Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29924	Hmn-214	GSE70138	NPC.CAS9	Human	24h	10uM	EID0129

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	BHLHE40; FOSL1; MYC; JUN; ETS1; FHL2; ARID5B; NPAS2; MAFF; MEF2A; ATF4; HIPK2; YBX1; FLI1; HIVEP1; ANKRD1; RELA; BACH2; CREB3L2; VGLL1; CREB3; BCL10; DEAF1; CREB5; HMGA1; ATF3; TGIF1; ELF3; NR4A2; NFE2L2; PAX5; FOSL2; SP100; IRF6; XBP1; ZBTB20; MYRF; LYL1; SOX10; EMX2; AES; IRF4; PAWR; ELF5; ZEB1; ST18; YBX3; TAL1; HDAC9; MYBL1; POU2AF1; KLF6; WT1; BASP1; ARNT2; ZBED2; ZFPM2; EGR2; TRIB3; FLNA
Down-regulation	94	CRK; BRCA1; EZH2; SOX4; SSBP2; TP53; PATZ1; SOX2; MYCN; CREB1; SUZ12; TFDP2; ZNF443; SALL2; RBBP4; DBP; HLTF; BRIP1; ZNF85; ITGB3BP; YEATS4; PTTG1; ZNF432; BCLAF1; RLF; CDK2; BMI1; HSF2; MAFB; ZNF91; ZNF606; TRIM24; DDX5; ZNF184; SMAD5; ASCL1; ZNF14; CARHSP1; ZNF302; TAF7; ZNF573; APEX1; VEZF1; MYCL; ZNF430; ETV1; ID2; NUP62; BRD8; MNAT1; ZNF32; DEK; ZNF24; SMAD6; TOX3; MED6; ADNP; ING2; MAF; IRX5; HMGB3; EED; CBX3; CBX5; RBBP7; ETS2; RBPJ; HDAC1; HES1; AEBP1; NCOA1; PURA; ZNF232; BRD3; NR1D2; C1QBP; PFDN5; BCL11B; SIX1; ID3; SCAND1; FOXF1; TCFL5; NR2F1; ID1; MAGED1; ERBB2; PBX1; PCGF2; MSX1; IKBKAP; DACH1; SUV39H1; NFATC3