Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29859	Gsk-1059615	GSE70138	NPC.CAS9	Human	24h	10uM	EID0129

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	SMAD3; TP73; PRDM16; ALX4; TULP1; TSC22D3; ZNF549; SCRT1; HOXB1; TBX1; TEF; MEF2C; PRDM12; HIPK2; MYRF; CDIP1; NFIX; EN1; RFX2; ZNF33B; ZIM2; PLAGL1; NR1H4; JUN; ELF4; KLF15; ZNF10; EMX1; CBX4; NEUROG2; ZNF132; VDR; WWP1; BTG1; SOX1; ZBTB7C; E2F2; ZNF749; MLLT1; SP100; HOXA6; DLX4; FOXB1; NR5A1; HIC1; VGLL1; ZNF165; FEZF2; THRB; ZNF682; ZNF141; SP140; RARG; TGFB1; SMAD6; TLX3; REL; HOXB5; IKZF3; HOXA5; ZNF334; SOX18; HSF1; TCEA2; KLF3; PIR; SNAI2; CREG1; EPAS1; TCF21; FOXO1; IRF9; SRY; CEBPB; STAT4; NPAS2; TCEB2; PAX5; ZNF331; SIX3; ZNF415; ARNT2; MECOM; ELF5; ZNF580; TLE2; RBFOX2; RBPJ; BCL3; TWIST1; HOXC10; ZNF467; ZBTB38; RUNX3; WT1; TBL1X; LITAF; ZNF83; HOXB6; TFAP2A; SOX17; ZNF611; HOXA11; AHR; POU2AF1; FOXA1; MBD2; MITF; INSM1; HOXB2; RORA; TRIM22; SMAD7; TXNIP; PAWR; SOX13; IRF6; EHF; ZBTB16; SPIB; OSR2; KLF9; PITX1; MYBL1; PEG3; KLF6; FOXF1; HOXC6; ATF3; HOXA10; TRPS1; ZBED2; GATA6; EMX2; NR1H2; CEBPD
Down-regulation	101	SSBP2; NRIP1; CCNA2; HMGA2; RBM14; NPAT; TCF12; BCLAF1; TRRAP; PMS1; RBBP4; BRD3; DEK; RBBP8; PATZ1; NRF1; BLM; RNF138; ORC2; BAZ1B; NCOA1; HMGB1; CHD1; ZMYND11; TCF7L2; HMG20A; SFPQ; SALL2; ZEB2; APEX1; ZNF22; PSPC1; SPEN; MAML1; PSMC3IP; WHSC1; JARID2; ATF7IP; USF2; XBP1; DMTF1; ZBED1; E2F6; RBM39; PBRM1; CBX5; TOX; HMGN3; MAX; KAT7; UBP1; ID4; KMT2A; CRY1; TAF7; HMGB3; PLAGL2; ISL1; MGA; ING3; DNMT3B; ASCL1; DAXX; SMAD4; SCAND1; KLF10; MYB; ASH2L; MYCL; EDF1; NKX2-1; ERBB2; MAGED1; DLX2; KAT6B; BAZ2B; MTF2; TAL1; CHD7; PAXBP1; DACH1; NR1D2; TAF9B; ID3; IRX5; ZSCAN18; PAX6; PRKDC; CENPF; NFIB; ZMYM2; SIAH2; ZNF589; PBX1; ERG; PSIP1; MNDA; LEF1; SOX9; BASP1; SUV39H1