Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29773	Vorinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0129

Response Information :

Types	Number	Response transcription factors
Up-regulation	113	IKZF1; DRAP1; FOXO4; MYCBP; FOS; EGR1; CREG1; STAT1; RUNX3; PPARD; RUVBL2; SERTAD2; GTF2A2; ARNTL; FOSB; PSMD9; BCL3; KLF2; EZH1; SIX1; IL16; DLX4; C1D; ZNF593; LDB1; CBX7; CEBPB; TGFB1; HDAC5; JUN; ZNF394; MLXIP; HBP1; HTATIP2; SPIB; HDAC1; SETD3; CITED2; CREM; TSG101; IRF9; SOX10; HMGA1; TCF15; SIRT2; HMG20B; TCF7; STAT4; HOXA10; HHEX; AHR; SND1; JARID2; JUNB; ZNF224; CTR9; CDYL; ZBTB7A; TERF1; LYL1; NR4A1; BCL10; TOB1; ZNF331; EP300; SATB2; SP110; NPAS2; NR1H4; TFAP2A; NR4A2; ITGB3BP; TBPL1; ETS1; IRF7; MBD2; NR5A2; SNAI2; HOXD1; ZNF580; FOXC1; KLF10; NR3C2; SIM2; SP100; WWTR1; ZNF652; NKX3-1; CEBPD; HLTF; PBXIP1; EGR3; TOX; SMARCA2; TCF21; LMCD1; CD3D; MITF; PTRF; OSR2; ATF3; SMARCD3; MYBL1; JUP; CUX1; NFE2; TP63; ZBTB20; LITAF; ERG; TRPS1; BASP1; PSIP1
Down-regulation	205	HMGA2; TP53; PCBD1; EZH2; SMARCA4; USP22; ATF1; TCERG1; HDAC2; HNRNPD; FOXM1; PATZ1; CREB1; BRIP1; SMAD3; ZFP37; WDHD1; ZNF282; ZBTB38; CCNA2; GTF2IRD1; STAT5B; NUP62; BCLAF1; ZBED1; ZNF227; ZNF84; RFX7; RBM39; GTF2I; HDGF; NEUROD1; ASXL1; MYCN; TAF9B; RBBP4; SALL1; PCGF2; APEX1; YEATS4; TRAK1; TAF1D; PHF2; CTCF; DDX5; DDX17; ZMYND11; PMS1; SOX11; NFKBIA; ZIC3; MEIS1; GABPB1; ZFP64; PLAGL2; ETV1; RBL1; ZNF146; RNF138; BRCA1; WDR77; ZNF302; TRIM24; PBX3; SP3; GLI2; ZNF432; DEK; PBX1; NHLH2; ZFY; ZNF112; ZBTB1; PMF1; MLLT10; ZFP69B; ORC2; NCOA6; NRIP1; WHSC1; TCF12; ZNF219; ZFP30; ZNF202; CBFB; LIN28A; ZNF189; ZNF177; NONO; CNBP; TEAD1; REPIN1; SMARCE1; ADNP; ZNF232; ZNF532; HMGB3; SSRP1; ERBB2; ZNF266; MNT; CNOT2; PAX6; NCOR1; TBL1X; HIPK3; NKX2-2; DEAF1; ZNF43; SMAD5; GATA4; ZNF140; ZNF334; ING3; SMAD6; BRD7; RBPJ; PSMC3IP; ZKSCAN7; PBRM1; ISL1; KLF7; CBX5; CHD9; SFMBT1; ZNF32; HMGB2; TCF4; BATF3; BCL6; TGIF2; E2F3; MED17; CARHSP1; ZBTB14; ZNF443; LZTS1; BAZ2B; ZEB1; RBBP8; ZNF22; VPS72; MEIS2; ZNF93; NCOA2; HLX; FOSL2; POU5F1B; ZNF134; HOXB6; DMTF1; TFDP1; ZNF423; NANOG; OLIG2; BACH1; SALL2; SMARCB1; PITX2; XBP1; ASCL1; MECOM; PHOX2B; SIAH2; MYCL; NCOA1; BAZ1A; ZSCAN31; ST18; ID4; ID1; NFE2L2; VGLL4; FOXL2; TRIM22; AR; INSM1; ZFPM2; FOXN3; MYBL2; IFI16; SCAND1; TOX3; TRIM29; NR1D2; LOXL2; ID3; YBX3; ZMIZ1; FOXF1; TLE4; MAGED1; NR2F6; SOX17; HOXB2; MYB; LEF1; MTA1; ZIC1; EMX2; ESR1; DACH1; SUV39H1; NFATC3; E2F2