Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29696	Hmn-214	GSE70138	NPC.CAS9	Human	24h	10uM	EID0128

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	FOSL1; ETS1; MYC; FOS; MAFF; FHL2; ANKRD1; ARID5B; TRIB3; ATF4; XBP1; PDLIM1; NR1H2; PPP1R13L; POU2AF1; POU4F1; EN1; TGFB1I1; BIRC2; SP100; MBD2; VGLL1; SOX10; JUN; ATF3; KLF6; ARNTL2; PTRF; ELK3; ZEB1; FLI1; LYL1; ERG; CREB5; CREB3L2; MYBL1; IRF6; LITAF; HHEX; NFIB; NPAS2; SMAD7; ZHX2; LOXL2; CEBPG; TAL1; ELF5; SERTAD2; KLF2; RORA; BACH2; JAK2; EMX2; LMCD1; JUNB; ZBTB38; PPARG; ARNT2; ZBTB20; TFAP2A; FLNA; WWTR1; SATB2; BASP1; PEG3
Down-regulation	97	ATF1; EZH2; SOX4; MEIS1; BRCA1; EED; PATZ1; NUP62; PARP1; RBBP4; GMNN; BCOR; CBX5; NONO; SUZ12; EHMT2; PLAGL2; CCNA2; SALL2; GLI2; SOX2; PUF60; HDAC6; MNT; DNMT3B; ID2; ADNP; APEX1; BRIP1; HIC2; JARID2; ZBTB24; WDHD1; ZNF443; HMGXB4; MYCN; PAX6; ITGB3BP; HMGB3; BRD8; ETV1; HDAC1; HNRNPD; ISL1; HSF2; PBX1; TRIM24; NAB1; RARA; CENPF; RCOR3; HMGN3; MAML1; RNF4; SMARCC2; DBP; CARHSP1; NR2F1; NPAT; WHSC1; SSBP2; ASCL1; HMG20A; SMARCE1; PBX3; TCFL5; RERE; ETS2; ZBED1; CBX3; PTTG1; SCAND1; BAZ2B; ZMYND8; SMARCD3; ING2; BRD3; CREG1; HLTF; RXRA; MYB; MYCL; HES1; TWIST1; MAFB; ZBTB18; SOX11; ZNF217; LEF1; ID1; MAF; TSC22D1; SOX9; CITED2; WT1; SUV39H1; PSIP1