Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29551	Vorinostat	GSE70138	NPC.CAS9	Human	24h	10uM	EID0128

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	FOXO4; EGR1; MYCBP; NR1H2; DRAP1; STAT1; FOS; CREG1; GTF2A2; TSG101; ZNF331; PHF1; NR4A1; RXRB; PPARD; FOSB; IRF7; SETD3; EVX1; CCNH; MEF2D; NOC2L; HMG20B; TCF15; ZNF224; TGFB1; APBB1; ZNF593; HABP4; CEBPE; SIX5; RUVBL2; CALCOCO1; HDAC1; PSMD9; CTR9; NR4A2; ZNF394; JUNB; LDB1; EGR3; PCGF1; ZNF205; CBX4; SP100; GTF2F1; NR4A3; DLX4; MNAT1; SIX1; TSC22D4; HDAC5; BAZ2A; ARNTL; KLF2; ZBTB7A; PPP1R13L; UBE2B; IRF3; COPS5; HDAC7; BBX; TAF10; SUPT5H; HMGA1; MXI1; TOB1; FOXJ1; CEBPB; POU4F1; HBP1; SMARCD3; RBBP5; CBX7; WWC1; SP110; CREM; C1D; SERTAD2; TCF7; ATF3; SIRT2; MBD2; ETS1; HOXD1; DDIT3; RUNX3; BCL3; ETV5; MYBL1; MLXIP; ZBTB20; VDR; ARNT2; NFAT5; SPIB; FOXC1; JUN; NR3C2; TBPL1; SMARCA1; SOX10; CRYM; ELF3; RORA; EHF; BRD2; TRIB3; BRD4; SNAI2; TFAP2A; AHR; NFE2L2; YWHAB; TP63; PAX5; SATB2; MNDA; TSC22D1; NFIB; NKX3-1; CITED2; MEF2C; BASP1
Down-regulation	183	HMGA2; NRIP1; PCBD1; SOX2; EZH2; XBP1; ATF1; SMARCA4; TCERG1; HDAC2; NUP62; CCNA2; ADNP; TP53; ZMYND11; PATZ1; NFKBIA; ZNF84; GLI2; ZMIZ1; ZBTB1; SMARCC1; MLLT10; PARP1; GABPB1; DEK; BRIP1; BCLAF1; HDGF; RFX7; ZNF22; ZNF282; ZBED1; PHF2; USP22; TBL1X; TFDP1; ZFP64; ZNF43; LIN28A; HNRNPD; SETDB1; MTA1; HMGB3; VGLL4; APEX1; SALL1; ZIC3; CREB1; PLAGL2; PMS1; SOX11; ETV1; ZBTB14; HMGB2; MEIS1; BCOR; ZNF85; BAZ1A; NCOR1; TAF9B; PMF1; NFYB; CBX5; ZBED4; ZFP36L2; VPS72; MYCN; ZNF227; ZNF532; ZNF232; BPTF; TRAK1; C1QBP; ZNF202; HIC2; ZKSCAN7; WDHD1; PBX1; MAGED1; SALL2; SAP30; YAF2; CUX2; ID4; ZBTB24; RAN; PCGF2; WDR77; RBM14; ZNF140; ZNF253; ZNF711; FOXM1; ZNF93; ZEB2; ZNF33B; BATF; KDM5D; RBBP4; MED17; CARHSP1; ERBB2; CTCF; REPIN1; KLF9; TRIM22; CREBZF; SIAH2; ZNF32; GTF2I; ZNF146; MYB; FOXE1; ZFPM2; SMARCE1; DDX5; SP3; PBX3; TCF4; ZHX2; BRD3; SOHLH2; ZEB1; ZNF292; RNF138; TAF9; NANOG; RBM39; WHSC1; ASCL1; ZNF107; NEUROD1; TGIF2; CTBP1; SFMBT1; PAX6; TGIF1; DDX17; HIPK3; SMAD3; ZNF302; HMGB1; TCF7L1; MKL2; ZSCAN31; TAF1D; AEBP1; ARL2BP; HIRA; HOXB2; CBFB; NCOA2; FOXO1; TOX3; DNMT3B; NCOA1; KAT2B; ZNF134; PITX2; BMI1; ZIC1; IFI16; ZSCAN18; NR2F2; CHD7; ZNF423; TCF12; HEY1; MYBL2; GATA6; HOXB6; EMX2; HMGN3; TSC22D3; PIR; ZFP36L1; LEF1; MEIS2; MAF; INSM1; SUV39H1; PPARG