Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29515	Kin001-127	GSE70138	NPC.CAS9	Human	24h	10uM	EID0127

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	ST18; PPARG; SUPT6H; HOXA10; ZNF512B; JUP; YBX3; TRIM29; FOXO4; ATF3; ELF3; PCGF1; CALCOCO1; CREG1; DDIT3; RNF6; ZNF264; IRF6; CBX7; BCL11A; CNOT3; NR3C1; FHL2; ZNF224; TRIB3; ZNF91; SRCAP; ZNF665; PBXIP1; MXI1; PNRC1; BNC1; BHLHE41; PHF1; TFAP2C; HDAC5; EN1; ZNF83; SAP18; IRF9; ELF4; TLE2; FOXF2; SUPT3H; PQBP1; TP63; SNAI2; TRIP6; JUN; HOXB2; ERF; TOB1; OVOL2; RREB1; VDR; TDP2; HIRA; IRF7; WWTR1; ZBED2; TFAP2A; LITAF; ZNF544; ARNT2; KLF5; TRPS1; AHR; KLF10; CEBPB; SERTAD2; OSR2; HHEX; ZFP36L2; MNDA; INSM1; TGFB1; HOXB6; HOXB7; IRF1; TWIST1; HOXD1; DACH1; ID1
Down-regulation	62	HMGA2; EZH2; CCNA2; BRCA1; RHOA; PSMC3IP; WDHD1; BLM; TRRAP; RBM14; CBX5; CENPF; SMARCA4; BAZ1B; BCLAF1; THAP11; CBFB; ETS2; HNRNPD; WHSC1; ZMYND11; PRKDC; SMARCE1; BATF3; EDF1; RBBP4; MAGED1; AFF1; CBX3; SMARCA5; PIAS2; ZEB2; PURA; ENO1; ID4; DEK; BRIP1; BRD3; PIR; ISL1; SALL1; KLF9; ASCL1; AEBP1; TOX3; CHD7; DNMT3B; BMI1; LEF1; XBP1; ING3; FOXO1; SAP30; NR2F1; SIAH2; MSX1; SOX11; HMGB3; MYB; SSBP2; HOXC6; KDM5D