Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29321	Olaparib	GSE70138	NEU	Human	24h	0.12uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	115	IRX5; MAGED1; BRD8; TCF4; WHSC1; SMARCA4; MEIS1; ZSCAN18; CASZ1; TCF20; SOX2; CTR9; FOXK2; ZNF430; GRHL2; MED6; DDX5; HLTF; NEDD8; EZH2; ZBTB18; NCOR2; ID1; TULP4; ZNF148; ZNF84; PBX3; BHLHE41; HDAC5; BCL11A; FOXO4; FOXJ1; HDAC6; ASH2L; TLE4; HMGB3; HDAC2; HIVEP2; NPAT; WWC1; SOX12; ZKSCAN1; NCOA4; ADNP; NKX3-1; ID4; HSF2; FOXJ3; BMI1; TRIM16; EP400; RFX5; GTF2IRD1; NUP62; RBPJ; MYCN; NCOA6; SERTAD2; RERE; ETS2; KDM2A; RBBP7; TBP; ASCL1; MYT1L; ARID4A; BAZ2B; HMGN3; NONO; DNMT3B; ZNF329; DACH1; NR1D2; RBBP8; TSC22D1; ZNF131; NFE2L1; PUF60; CRY1; SPEN; CITED1; RCOR1; ZMYND8; HEY2; CHD3; RLF; LEF1; FOXD1; CAMTA1; CNBP; HTATIP2; MYB; KDM5D; ARID4B; MED13; ELF5; RBBP4; SMARCA5; INSM1; SSBP2; ZNF264; WWTR1; EYA1; PCGF2; VGLL4; MTF2; ZMIZ1; MTA1; DRAP1; ABL1; CHD7; NRIP1; WT1; SOX11; CRK
Down-regulation	147	ARNT2; HOXB9; GFI1B; DOT1L; SMARCC1; POU4F3; FOXB1; FOXD3; KDM5B; EMX1; VENTX; LHX3; RFX1; HOXB1; ZNF467; PAX3; ZNF391; KLF12; KLF4; ATOH1; FEZF2; HMGA1; ZNF780B; UBTF; SOX3; STAT4; ZNF23; NR5A1; POU4F1; ZNF331; SRY; IL16; BACH1; ZNF749; SPI1; SIN3B; HOXD11; ZBTB25; RXRG; MNX1; KLF11; ZNF688; SOX5; SIM1; KLF15; THRB; CDX1; ZNF771; CAPN15; CBX2; SOX18; TCF3; ITGB3BP; JUNB; JAK2; THAP11; GATA1; PPARGC1A; BRD2; RNF138; TGS1; POU4F2; FHL5; SMAD7; CEBPG; IRF3; NR4A3; ESR1; CDIP1; FOXI1; SOX13; NR5A2; ARL2BP; CCNC; FOS; ERF; TCF21; LITAF; HIPK2; CEBPD; CBX7; WWP1; AHR; FOXJ2; MDM2; SSX1; PTTG1; TRIB3; ACTL6A; MBD2; ATN1; GATAD2A; NR2F2; PSIP1; IRF7; MAF; ZNF573; NR4A2; TFAP2A; SMAD1; HOXA10; SATB2; ZEB2; IRF6; TAL1; KAT2B; CD3D; SSBP3; LMCD1; CREM; MEOX2; CREB3L1; ZFP36L1; MAFB; AR; TRIM22; STAT1; ZBTB20; NFKB2; VDR; SPIB; SALL1; CBFB; HMGA2; SUB1; JUP; CDK2; FOXA2; DMTF1; FOXO1; ZMYM2; TGFB1I1; LOXL2; MYBL1; ATF5; IRF9; GATA6; MNDA; NFAT5; ZBTB16; YBX3; MITF; BTG1; ZNF589; KLF9; EGR2; TOX