Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29319	Olaparib	GSE70138	NEU	Human	24h	1.11uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	147	ZBTB1; ZBTB11; PHF20; TBL1X; BRD8; L3MBTL1; NFATC3; ARID4A; HSF2; ENO1; KMT2A; TBPL1; HDAC6; NR2F2; MNT; NCOA6; TCF20; VEZF1; ABL1; DNAJC1; CRY1; TOX3; NCOA1; BRD3; REPIN1; SMAD2; IRX5; ADNP; POU3F2; SOX2; FLNA; TSC22D2; TCF12; ZNF302; SP3; TCERG1; SAP18; NR3C2; BTAF1; FUBP1; BMI1; NUP62; SMARCE1; KDM5B; HOXC6; PURA; DPF2; PATZ1; MAGED1; MED23; MED1; TAF1D; BASP1; SMARCD3; PCGF2; MAFG; HMBOX1; CDC5L; PQBP1; CDK8; NR1D2; TRIM32; HIVEP2; SMARCA4; ZMYM2; KAT8; YWHAB; FOXJ3; SIM2; TCF4; BPTF; GTF2IRD1; ZNF24; HMG20A; HNRNPD; NCOR2; WWC1; MLXIP; TBP; RAN; NEDD8; ETV1; HSBP1; ADNP2; ZMYND8; MAFB; SIAH2; BATF3; PSPC1; RLF; JARID2; RCOR1; RNF138; EDF1; CBX5; LEF1; ZBTB43; HDAC2; BCL11B; CTR9; RBBP7; RBBP4; ZNF329; ZEB2; HMG20B; NFAT5; ARID4B; ZNF32; PEG3; BTG1; ZNF532; ZBTB38; SMARCA5; TOB1; DACH1; SSBP2; MEIS1; SAP30; TCEA2; VGLL4; ID4; CHD7; SPEN; KLF5; PUF60; NFIB; MYCN; MTF2; TCF7; LMCD1; ZNF91; CHD9; RFX5; INSM1; SOX9; CARHSP1; EGR3; HEY2; SATB2; ZMIZ1; HLTF; PSIP1; NRIP1; KDM5D; MAF; SOX11; CRK
Down-regulation	239	MEIS2; SKIL; TAF4B; ALX4; SOX14; ZNF549; RFX1; ZNF154; TLX3; TP73; LIN28A; SCRT1; FOSB; JUND; GATA4; ZNF142; HNF4G; ZNF749; NEUROG2; KLF8; NACA2; FOXD3; ZNF695; ATN1; UTF1; FEZF2; POU4F3; PRDM14; MEF2A; TRIP11; ZNF780B; SOX13; GBX2; FOXH1; KLF1; IRF2; FOXC2; TAF1C; GRIP1; POU6F2; SSX7; ZNF528; NPM1; TAF6L; LHX3; ZNF225; ZNF771; POU1F1; ZNF674; ZKSCAN4; ZNF391; HESX1; ZNF81; TEF; LYL1; PAX4; CALCOCO1; JUNB; NR5A2; ZBTB3; TULP2; GFI1B; ZBTB48; SOX18; HIPK2; TAF12; TCEA1; ATOH1; VENTX; VGLL1; CALR; CARF; SRY; ZBED2; BNC1; POLR3C; OVOL1; AIRE; DLX6; RBL1; E2F4; MYBBP1A; ZNF507; EN2; TTF2; SIX3; NANOG; TEAD4; TAF7L; SHOX; HOXD9; CAPN15; TDRD3; BRDT; TFCP2; CHD2; MYEF2; HOXD10; TAF5L; DLX5; SSBP3; IKZF3; ZIC3; TBX5; ATF6; PRDM1; SOX15; GATA1; SOX10; ERF; FOXI1; TAF1; ADRB2; THRB; CDK2; RARB; BARX1; ARRB1; CEBPD; FLI1; IRF6; PPP1R13L; SOX21; ZNF557; TRIM22; ZNF675; MYNN; TCF7L1; TGS1; TP63; PA2G4; ZNF141; TGFB1; RBPMS; KDM5C; ZNF215; TAL1; SP140L; CREM; MYRF; HSF1; HOXB2; MYBL2; ZNF623; TCF21; ZNF394; ATF3; SPI1; FOXL2; NFE2L3; JUN; NR1H4; HMGA1; REL; FOXM1; MAFF; KLF4; NFIC; TFAP2A; STAT6; HOXD1; MED14; GCFC2; ZNF552; CIITA; E2F8; ZNF117; ZNF264; KLF6; SPIB; NR2F6; TFCP2L1; ID3; PGR; BNC2; FOXF2; ID1; TERF1; ZNF33B; IRF1; TP53; TAF10; PNRC1; MYBL1; ACTL6A; NR4A3; PBXIP1; ARNTL2; NFATC4; CREBL2; NPAS2; CNOT3; TFDP2; YEATS4; KLF2; HES1; EPAS1; SUPT3H; NFE2; IFI16; ST18; HEY1; PITX1; ZFP36L2; ZHX2; SLC2A4RG; TDP2; GATA2; BCL11A; RUNX1; PTRF; DMTF1; HDAC9; KLF7; ZNF195; HOXA1; SOX17; LITAF; ESR1; WWTR1; HOXC10; HOXB7; ZNF423; NFKB2; SPDEF; LOXL2; PIR; ZNF589; NR1H3; JUP; ELF3; SMAD6; ZFPM2; ELF4; TRPS1; WT1; GATA6; ETS1; KLF9