Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29310	Tie2-kinase-inhibitor	GSE70138	NEU	Human	24h	0.04uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	148	HAND1; NKX3-2; SNAI1; RBPMS; IKZF1; NR1I3; TWIST1; TOX3; TAF4; RARA; ZNF384; ELK3; E2F6; NFKB1; BRCA1; EGR4; NKX2-2; FOXF1; MNT; ARID5B; GCM1; PLAGL2; CTR9; RNF141; SMARCA5; SUV39H1; ETS2; NFX1; ARRB1; DMRT1; MTF1; TTF2; ITGB3BP; ENO1; PRRX2; PHF8; HOXA1; NOCT; BAZ1B; CDIP1; EN2; CAMTA2; RFX2; BRDT; GFI1; SHOX2; FOXD1; TCF12; ATF7IP; SFMBT1; VDR; YBX2; PRDM1; RUNX1; TBL1X; PLAGL1; NFIC; NAB2; DPF2; SAP30; CREM; DLX2; BAZ1A; SMARCE1; DLX4; ZNF177; ARNT; HOXB7; TFAP2C; HLF; SMAD1; IRF1; STAT6; MED12; STAT4; KLF10; RUNX3; VEZF1; TGFB1; ZNF267; WT1; NEUROD1; CREB3; NCOA2; TSC22D2; FOXI1; NFIX; MSX1; MDM2; PIR; ETV5; RBPJ; CIITA; SSX1; OVOL2; NFYC; MYBL2; DNAJC1; IFI16; ERBB4; OSR2; ZNF652; KLF7; HMGA2; BMI1; IRF8; ESR1; HOXC10; KLF9; RFX5; GLI3; TFEC; NR2F1; ATF3; TCEB2; RBBP8; ELF3; TULP3; SOX9; SMAD3; NR1H3; NR4A3; YAP1; ELF4; TRIP6; HOXD1; EHF; CALR; HOXB2; CCNE1; AFF1; DLX5; CITED2; FOXO4; VGLL4; CRK; GATA6; MYB; MBD2; ST18; TRIM22; TFAP2A; TRIB3; MKL2; MEIS1; HOXB6; MITF; MECOM
Down-regulation	186	USP21; NCOA1; NPM1; ZNF544; TBL1XR1; ZBTB14; CHD1; BTF3; ZIC1; ZSCAN18; ZNF24; ZNF8; UIMC1; TAF1A; ZNF562; PSPC1; PFDN5; FOXN3; ING3; KAT6B; HDAC3; NRF1; WHSC1; NR2F6; ZSCAN16; NRIP1; BRD3; THAP11; RNF10; RBM39; FOXC1; FUBP1; ZNF358; MTA1; ZNF134; ZNF268; ADRB2; YBX3; PBX3; AIP; CCDC59; E2F5; PTTG1; SCAI; CNBP; PUF60; BACH2; PATZ1; PKNOX2; CENPF; FOSB; GTF3A; BBX; ZNF84; NR2C1; TBX2; MLX; ZNF506; KLF1; PBX1; ZNF350; ZNF580; CHD8; ZNF83; SF1; ZZZ3; HEY1; HMGN3; UBE3A; ZNF573; JAK2; ZNF302; NFYB; MYCL; HMGB1; PEX2; ZNF32; ZBTB11; DACH1; HDGF; KDM4C; TAF9; CNOT2; ZNF292; ZNF529; GCFC2; TBX3; BHLHE41; HOXA5; ZNF354A; DEK; RAD21; CTCF; BCLAF1; TRIM29; TAL1; SSRP1; HSF2; NR4A2; ABL1; DMTF1; TCF15; MTF2; BNC2; IKBKAP; HDAC4; ZNF211; KLF13; ZNF331; CSDE1; ZNF419; ZNF219; CIZ1; RFXANK; SAP18; ID2; RBBP4; SALL2; BCL6; TAF7; ETS1; PCGF1; TCEA1; ID1; ZNF468; ZNF551; MAF; NEDD8; ARID4B; SSBP2; ZNF432; MLXIP; CTBP1; RAN; TRIM28; TSC22D1; ZKSCAN7; PHIP; BCL11A; SUPT3H; NAB1; HEY2; ZNF329; JUN; STAT1; CEBPB; SMARCA1; BTG1; TRPS1; PRKDC; ZMYM2; PURA; ID4; TP63; TLE4; MAGED1; NFIB; ZNF189; NFE2L1; NR4A1; PSIP1; ZMYND8; ZBTB20; POU2AF1; EGR1; MXI1; TOX; BAZ2B; ZNF131; EYA1; ZNF12; EYA2; ZFP36L1; APEX1; LMCD1; ATF4; ZNF43; BIRC2; SALL1; NR1H2; ZEB2; TCF7; FOXJ3; ZNF423; SOX11; KDM5D