Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29309	Tie2-kinase-inhibitor	GSE70138	NEU	Human	24h	0.12uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	137	ATF7IP; YEATS2; TAF9B; ZNF692; DLX5; SUV39H1; BRF2; HOXA1; TWIST1; PHF8; ARHGAP35; MNT; JUNB; RELA; ELF4; RNF141; STAT2; ZFHX4; SMAD1; IRX4; FOXE1; DNAJC2; GRHL2; ZNF574; ZBED2; MEOX1; PREB; HTATIP2; DEAF1; EHF; TAF4; RBL2; PIR; HIVEP1; BATF3; GLI2; CTR9; HOXC10; TLE2; ZBTB24; ZNF589; RUNX1; MAFB; PIAS2; DPF2; PLAGL2; PURA; SOHLH2; ZHX3; ARNTL2; CDK7; CCNE1; ETV1; SIX1; BACH1; ASH2L; HIC2; PIAS3; WHSC1L1; HES1; MSX1; MECOM; SREBF1; SIM2; SRCAP; SKI; ZNF443; LHX6; SAP30; IRF7; SMAD5; CBX6; TFEC; OVOL2; KLF3; NFKBIA; RUNX3; ZNF394; EYA2; GLI3; ETS2; MAGED1; CRY1; ELF3; ZNF165; FOSB; TAF9; FOXO4; MKL2; TRIM29; NR1H2; KDM5D; TP53; WWTR1; PGR; FOSL2; CREBL2; MED21; PQBP1; ZNF217; CITED2; BRD4; ZNF264; FLI1; MLXIP; MYCN; AFF1; ERG; ZNF652; MBD2; TFAP2C; ASCL1; CUX2; BCL3; TRIP6; MITF; TRIM22; E2F3; SMARCA5; MYT1L; BMI1; BASP1; TOX3; NR1H3; IFI16; PITX1; ETS1; MTA1; CRK; ID3; TXNIP; JUN; DRAP1; PSIP1; TRIB3; NR2F6; ARID4B
Down-regulation	130	HMGXB4; MXI1; KAT6B; SP3; ZNF8; CDX1; ZBTB20; RRN3; RORA; STAT5A; CSDC2; RCOR3; EN1; TAF1A; TBX2; HMBOX1; SOX3; RAD21; TBX3; CHD9; TCEA1; HBP1; RXRG; PPARGC1A; CLOCK; TFEB; ZNF410; SUPT4H1; MTF2; REL; NRF1; ZNF580; NFE2L3; TCF21; ZZZ3; SOX10; UBE3A; DACH1; EMX2; CNOT1; ZNF34; XRCC6; BPTF; SPEN; HOXA5; HMG20A; GATA6; SIX3; STAT5B; ZNF24; HMGN3; CTBP2; PITX2; CNBP; KLF1; ID2; ZFP36L1; CARHSP1; MED1; BTF3; SOX9; ZMIZ2; PUF60; CBFB; CHD1; PKNOX2; CTNNB1; HLF; GATAD2A; NR2F1; HHEX; ZEB2; NCOA4; ZBED4; NKX3-1; ZNF22; MYBL1; ZMYM2; ZNF551; ZNF544; KLF11; RYBP; HOXD1; ZNF12; CD3D; PSPC1; SSBP2; LITAF; PSMC3IP; MED13; TGIF1; SAP18; CTCF; CHD7; TGFB1I1; PHIP; THAP10; HIPK1; RBM39; ZNF32; ID4; THAP11; DAXX; RFX5; FOXF2; SMARCA1; BAZ2B; TCF7; YBX3; CNOT3; NR0B1; RNF138; ARID1A; MYCL; PTRF; SUB1; INSM1; ZNF331; FOXJ3; GTF3A; MYRF; RBBP4; ABL1; LMCD1; IRF6; ZNF423; ZNF131; ATF4; ZFPM2; PBX3