Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29308	Tie2-kinase-inhibitor	GSE70138	NEU	Human	24h	0.37uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	EYA2; ATF3; NKX2-5; ZNF528; SMARCA2; DMRT1; ZNF835; YWHAB; GATA3; ELK3; MED20; FOSB; FOXD1; BRCA1; TOPORS; ELF3; GLI3; ETV1; SIM2; ZNF701; PRRX2; RNF141; SMARCE1; HOXA10; RBPMS; MNAT1; MECOM; SMARCA5; ZNF415; POU4F1; NFIX; TWIST1; ZSCAN31; PRDM5; NR1H3; NFE2L2; ZNF556; RBM14; RBPJ; ASH2L; NHLH2; TXNIP; TRIM16; YBX2; MYCBP; BRD2; ZNF552; FOXL2; EDF1; BRPF1; WWC1; LPIN2; TRIM22; JUNB; CIR1; LITAF; LHX2; HOXC4; AHR; WT1; PIR; ZNF783; ATF5; NEUROD1; MAFF; PURA; KLF4; ARNTL2; CREB3; ZNF165; WHSC1L1; PA2G4; NPAT; ENO1; SIX1; ZNF302; SOX10; GLI2; ZNF665; MAF; STAT4; HOXC10; ZHX3; EN1; HOXC6; OSR2; HMGA2; KDM5D; MYC; LZTS1; ING2; HES1; DLX5; NFATC1; DDX5; SSX1; ESR1; TFAP2C; ST18; MITF; IFI16; STAT6; MAGED1; BNC2; CTR9; TFDP2; VGLL1; FHL2; PAX8; BASP1; RBL2; ZNF274; NKX3-1; RUNX1; ELF4; HMGB3; SNAI2; LOXL2; KLF10; PITX1; ID4; CRK; PEG3; IRF6; ZNF217; ELF5; VGLL4; HLTF; MYB; PSIP1; DRAP1; SOX9; NFIB; GATA6; ZNF91; TRIB3
Down-regulation	227	MEIS2; IKZF5; CHD1; SP110; ING3; ARID1A; PNRC1; PEX2; ZNF410; TCF3; RCOR3; AGO2; UIMC1; ZBTB7A; ZBTB17; CIC; HDAC3; COPS2; CTBP1; RFC1; HDAC4; TBX3; KAT6B; ARNTL; ZZZ3; SIRT7; KLF13; FOSL2; NCOR2; ZNF710; MTA1; PATZ1; BPTF; ZFHX3; REPIN1; CREB1; ZBTB16; SAP130; FOXK2; RNF111; ERCC3; PHF20; FOXJ2; MYCL; MLLT10; CBX4; ZKSCAN5; NOC2L; SUPT6H; MKL1; SPEN; SIN3B; KAT2A; ATOH1; UBE3A; TBX10; PFDN5; SUPT5H; ZBTB32; ZNF34; CNOT3; ZMIZ2; TCEA1; HBP1; RYBP; SF1; POLR3C; ZNF467; ATN1; MED17; ZNF696; SOX3; USP16; TBL1XR1; MEF2A; ZNF107; E2F8; HSF1; BRCA2; ASCL1; ERBB4; CAPN15; GTF2F1; TAF1C; TFEB; CENPB; EYA1; HIPK1; PSPC1; ETV4; NR2C1; TAF12; RCOR1; MAFB; SALL2; HIVEP1; HEY1; NR2F6; ARID4B; DACH1; AR; PAX5; NKX2-1; PBX3; TAF6; CNBP; SMAD4; ERF; RNF138; WHSC1; FOXN3; ZNF226; PUF60; CREBL2; SUPT4H1; PCGF1; SP2; MED15; AES; ADNP2; SOX13; ZNF580; SMAD2; THAP11; BCL11A; CERS6; SIAH2; C1D; RREB1; PAX6; POU2F1; RNF4; NPAS2; TSC22D1; ELF1; HDGF; NR1H2; CDYL; JARID2; CREM; SMARCC2; BAZ2B; KAT8; BCL6; FOXG1; TCF21; SRCAP; NFKBIA; ETS1; CCNC; ZMYND8; ZNF24; CRYM; LMCD1; SLC2A4RG; MTF2; IRF7; TCF7L2; BRD4; ZMYM2; DR1; SUPT3H; ZNF512B; ZNF239; FOXM1; LDB1; ZNF273; BRD3; TGFB1I1; MXI1; DMTF1; BBX; SALL1; ZNF432; FOXJ3; BCOR; TADA3; MNDA; KDM4C; KDM5A; HMGB1; RFX5; HOXB5; CEBPD; TRPS1; MED1; ZHX2; KLF5; HMGN3; BANP; ZEB2; ID3; HLX; CNOT2; HTATIP2; HOXD1; HOXA5; IRF9; ZNF12; ZNF85; SCAND1; ERBB2; CEBPB; SSBP2; STAT1; APEX1; CRY1; YBX3; TRIP6; ZBED1; THAP10; MEIS1; NFAT5; CBX3; NR2F1; PCGF2; SUB1; CUX2; CALR; POU2AF1; INSR; BTG1; ARID5B; RBBP4; CHD7; AEBP1; HIRA