Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29307	Tie2-kinase-inhibitor	GSE70138	NEU	Human	24h	1.11uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	ADRB2; NR3C1; ING3; ZNF711; ZNF14; IRX5; ZFP64; KDM5A; USP16; CHD1; BRPF1; BRD8; BMI1; PHF20; CRY1; MED1; NKX2-2; FLNA; PAX6; RLF; MYCN; ID3; IKZF5; PAXBP1; ENY2; RFX7; TCF12; MAZ; ZNF177; ABL1; PTTG1; NONO; HDAC6; EHMT2; JUNB; IKBKAP; AES; PHIP; KMT2A; HSF2; CAMTA1; BBX; HMBOX1; SAP30; ENO1; ADNP; ATF4; TRIM28; PQBP1; RCOR1; SIM2; DLX2; NCOA6; CARM1; ASCL1; ETS2; ADNP2; SMARCA4; ZNF593; SCAND1; ZNF443; TRIM24; HEY2; SFPQ; NEDD8; HDAC2; ZNF721; TOX3; PCGF2; HMGN3; ZEB1; BRD3; BTG1; SOX9; CENPF; FOXJ3; ZIC1; MAGED1; KLF10; ZNF160; NFIB; ZNF292; ZNF32; CHD7; ID1; SMAD6; TAF9; SSBP2; RBBP4; VGLL4; ZEB2; INSR; MSX1; JARID2; MYT1L; APEX1; BASP1; ARID4B; SPEN; NRIP1; HEY1; RFX5; TSC22D1; ZMIZ1; ZBTB18; NR1D2; TCF7; POU2AF1; MTF2; ZNF423; TLE4; ZNF131; PUF60; TXNIP; TOX; PSIP1; SOX11; KDM5D; CRK
Down-regulation	133	FOXO1; TCF7L1; NFE2; HOXC5; LIN28A; TEAD3; TRIP11; NFE2L3; TTF2; SRCAP; HOXB2; CSDC2; TRIM22; ZNF215; GATA4; CCNH; NANOG; RBPMS; FOXL2; IRF6; AR; IRF2; TFEC; ZNF507; STAT5A; ZNF75D; EHF; FOSB; BNC2; BRDT; CSDE1; MAFF; TBX5; PGR; TRIM33; TFCP2L1; RNF6; BRF2; BLZF1; THRB; MED14; VDR; STAT2; ZNF165; CEBPD; FOXA1; SKIL; NRBF2; ZNF623; SPI1; CDK8; TGIF1; ZBED2; NR4A2; FOSL2; TBX1; REL; EMX2; WNT4; RNF14; GLI2; STAT6; ELF5; NCOA3; ESR1; CREBL2; ZBTB16; COPS5; GRHL2; ZNF573; VGLL1; NFIX; CDIP1; FHL2; BARX1; FLI1; YAP1; TRPS1; NFATC1; PAX8; ZNF415; ZNF264; LMCD1; SNAI2; EGR4; WWP1; MYBL1; MAF; BACH2; HOXA10; PIAS3; HOXB5; ZNF331; HLX; CREB3L1; BCL6; MYCBP; ATN1; HES1; TWIST1; JAK2; ETS1; IRF4; KLF7; ACTL6A; ST18; SREBF1; NFATC4; STAT4; CTBP2; ATF3; MITF; KLF11; HOXB6; CRYM; IFI16; NR1H2; STAT1; CDK2; PIR; HOXA11; ZMYM2; TFAP2C; TBX3; SMARCA1; NFKB2; CITED2; PBX1; HOXC10; SALL1; CCNE1; EGR2; WT1