Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29279	Regorafenib	GSE70138	NEU	Human	24h	0.37uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	TBP; HMGXB4; COPS2; YAF2; HSF2; LEF1; SATB1; UBE2I; ZNF711; TOX4; PCGF3; MAFB; ZNF146; RNF4; MED24; RCOR3; ZNF529; CBX3; ZNF84; DDX17; RNF6; ZBTB11; ERBB2; HOXB7; ZNF593; CBX5; TOX3; MNT; BRD3; TRIM16; SMARCA4; MED23; MAX; MYT1L; SIAH2; RUVBL2; ZEB1; HNRNPD; CCNC; BMI1; ZBTB18; HLF; PHIP; IRF8; GTF3A; DNAJC1; HIC2; ETS2; ATF4; ATF5; PCGF2; NEDD8; ZMYND8; NONO; JARID2; CAMTA1; MAGED1; NR2C1; ARID4A; E2F3; RLF; ID3; ZNF292; ZMYM2; HOXB6; BASP1; TSC22D1; MXI1; PATZ1; HMGN3; MYCN; ARID4B; SAP30; ZNF131; FOXJ3; HOXC6; TLE4; APEX1; MTF2; SPEN; RBBP4; PBX1; ZFPM2; ZMIZ1; PSIP1; NRIP1; MNDA; PUF60; SSBP2; MTA1; PEG3; NR2F6; SOX11
Down-regulation	75	TBX21; REL; PRMT2; SNAI2; TRIP11; SIX3; MAFF; FOXM1; CTNNB1; BTG1; KLF6; SIX2; THRB; FOS; ACTL6A; OVOL2; ELF3; ZHX3; SOX13; MDM2; SP100; IRF6; ASCL1; ZBTB38; TTF2; ETV1; TP53; LHX6; EYA2; IFI16; BHLHE41; GLI3; POU4F1; GFI1; SOX10; EGR4; ESR1; YEATS4; SMAD7; PITX1; FOSB; MITF; HMGA1; NR4A3; SPIB; PAX5; TRIM22; PLAGL1; PTTG1; TP63; DLX5; MYCL; KLF4; HDAC9; FHL2; CRYM; FOXO1; SMAD1; MBD2; RUNX1; MECOM; SOX17; KLF9; TXNIP; SLC2A4RG; RUNX3; JUP; EHF; TGFB1; ZNF217; HOXC10; NR3C1; EGR1; NFATC3; KDM5D