Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29278	Regorafenib	GSE70138	NEU	Human	24h	1.11uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	182	TCFL5; HDAC1; TWIST1; SUZ12; SMARCE1; IL16; FOXD1; ETS2; PURA; L3MBTL1; DNAJC2; TMF1; KDM4A; ZNF652; MXD1; ZNF467; JARID2; ERG; HMGB2; ZBTB38; FOXF1; PBRM1; RARA; ENO1; PIAS3; ATF1; MED1; ELF3; ZNF835; SOX9; PPARD; TRRAP; ZFHX4; IRF5; ZNF721; NFAT5; BRD7; ING2; THRAP3; TAF9B; GABPB1; MED23; TBL1X; YWHAB; MED4; AHR; SMARCD3; GTF2A2; KMT2A; HOXC13; RBPJ; EZH2; PHF20; NFKBIA; PMF1; CBX6; TBPL1; MMS19; SOX5; TCEB2; PITX1; DLX5; TAF1D; URI1; ZNF165; SMAD1; GTF2IRD1; TULP4; TXNIP; ZNF587; SMARCA5; HNRNPD; BHLHE41; MED12; LDB1; E2F3; MLX; AFF1; PRKDC; RHOA; OVOL2; SP140; PRRX2; VDR; TLE4; CTR9; ATF6; SNAI2; NUP62; DPF2; STAT2; HSBP1; PLAGL1; ZNF282; EGR3; NPAT; PBX1; FLNA; HLTF; TERF2; FOXJ3; WNT4; DLX4; ZNF160; BNC2; KDM5D; NKX2-2; ZBTB43; NCOA6; MYB; CCNT1; BCL11B; MAGED1; PHIP; BATF3; DNAJC1; SMAD5; MED24; CBX5; NFE2; MNT; ADNP; TFEC; TSC22D3; CREB1; FOXO1; MYCBP; ELF4; ZMYND8; DDX5; SSBP2; NR4A2; MTF2; TOB1; SMARCC1; NFKB1; BATF; ZNF264; HMGA2; PATZ1; HOXB6; SREBF1; TRIM16; KLF2; TSC22D2; TOX3; RBL2; HLX; INSM1; CHD3; BASP1; RBBP4; TCEA2; PCGF2; ID4; ZNF274; MEIS1; MYCN; KLF5; CCNE1; PIR; NONO; MYRF; PAX5; TDP2; NR1D2; TFDP2; NFATC4; CITED2; DRAP1; MAFB; BMI1; MAF; SATB2; EGR2; PSIP1; TGFB1; MECOM; PUF60; MITF; SOX11; PEG3
Down-regulation	220	TLE1; KAT2A; RB1; ZNF22; KAT6B; ZNF45; YBX3; ZNF85; MEIS2; REPIN1; TAF10; FOXK2; MYF5; TTF1; FEZF2; ZNF146; BRIP1; BRCA2; HLF; TCF7L2; ZNF107; ZNF195; SRCAP; ZNF117; ITGB3BP; ZNF345; ZBED4; ZNF614; MTA1; BCL6; HSF1; NR1H4; ZNF227; VGLL4; MED15; NEUROD6; TAF4B; ZNF668; E2F8; ZBTB16; ZNF155; SPIB; ZNF180; CEBPB; LITAF; ZNF468; ERF; KMT2B; GCFC2; ZNF473; ZBTB7A; ING4; NR2E1; UBP1; NOC2L; ZNF384; ZNF177; ZNF354A; ZFP2; NRIP1; OLIG2; HMGXB3; BCL11A; NPM1; MED21; RFX5; SPEN; ZNF675; ZNF268; HDAC9; ZNF232; KAT8; ZNF235; HOXA7; ZFX; E2F4; HOXA4; TADA3; ZNF529; PEX2; ZNF140; HOXD9; ZNF32; ZKSCAN7; PCGF1; STAT6; CREB5; ZNF12; NFIB; THAP1; ZSCAN12; THAP11; TTF2; PAX8; IRF3; THAP10; HOXA5; ZNF580; MYBL1; RNF14; FOXM1; LHX2; EN1; ACTL6B; ZNF593; ZNF43; SUB1; CRK; SNAPC4; KLF13; FOXI1; ZNF226; ZNF263; PNRC1; ZNF410; TBX3; USP16; HDAC5; HIVEP2; ZNF573; LHX1; ZMIZ2; ZNF254; MZF1; ZNF273; ZNF500; TRIP11; MAZ; PIAS4; C1QBP; ZNF302; REL; CALCOCO1; KAT2B; PSPC1; FOXF2; MED17; GTF3A; UBE3A; PMS1; HOXD1; SALL1; KMT5A; ZNF544; SLC2A4RG; BCL3; TEAD4; IRF8; ATF5; ZNF557; GATA6; TSC22D1; PPARGC1A; DMTF1; HMGA1; CEBPD; TRIB3; CSDE1; ARID4B; ZNF239; BPTF; ZSCAN18; RREB1; ZNF10; CHD9; MEOX2; YEATS4; TFCP2L1; CNOT1; ZNF551; NR2F2; ERBB4; RBBP8; NR4A1; CITED1; FOSB; ATN1; BAZ1A; CNOT3; MXI1; POU2AF1; IKBKAP; TAF7; CBX3; ZNF131; RBM39; FOXG1; LMCD1; STAT1; KLF11; TULP3; CDYL; KLF7; RNF138; TGFB1I1; ZNF589; ZHX2; NR1H2; CAMTA1; YAP1; CUX2; HTATIP2; BRD4; RUNX1; ZFP36L2; ZNF91; EHF; CALR; SOX17; EMX2; MYCL; CARHSP1; ZMYM2; ATF4; IRF6; APEX1; NR2F6; DACH1; KLF9; ZNF423