Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29233	Alectinib	GSE70138	NEU	Human	24h	0.04uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	135	JUNB; USP16; CREBZF; FOXJ1; DAXX; IRF9; TRIP4; THAP7; MEF2A; HOXC4; ATF5; IRF1; IRF3; TERF2; PAX6; AEBP1; MED15; TAF6; CBFA2T3; NFE2L2; ZBTB7A; CAMTA2; YAP1; IRF8; ZNF34; ARID1A; CLOCK; CBX7; BHLHE41; BAZ2A; PRMT2; ZNF623; HOXA5; BRWD1; NR4A2; HHEX; FOXF1; ZNF124; NAB2; ACTL6A; PAWR; RNF6; MEOX1; SMARCA1; ZBTB20; HTATIP2; PDLIM1; ELK4; SIRT7; SMARCC2; CUX1; MKL2; HMGA1; ARL2BP; NFE2L3; ELF1; CNOT1; ATF3; KLF13; SHOX2; LOXL2; LEF1; MNDA; NR0B2; LITAF; PA2G4; MYBL2; ZBTB16; ZNF410; STAT1; ZNF394; CNOT3; FOXJ2; NR0B1; ZFPM2; MLXIP; AES; GCFC2; RBL2; EPAS1; ERBB4; TRPS1; KLF5; FLNA; CEBPG; THAP10; ZHX2; BRD2; CBX6; SLC2A4RG; TDP2; AHR; STAT6; HLX; CALR; KLF9; RORA; TGFB1I1; TOX3; NFATC3; INSR; ETS1; ID3; ELF4; TRIB3; HEY2; WWTR1; HOXC10; SOX17; SMAD1; CREB3L2; SPDEF; ETS2; CEBPB; HIRA; TFAP2A; TCF7; ZBTB38; HLF; CD3D; NR4A1; TOB1; ZNF232; SATB2; SOX9; MAF; NR2F1; NFIB; TGFB1; NR1D2; GATA6; MYBL1; JUN; ESR1; CRK
Down-regulation	116	SOX4; UBE2I; GABPB1; CTNNB1; TCEB2; NPM1; MED23; TRAK1; NRBF2; NUP62; ZNF268; USP22; ZNF146; BRD8; TAF10; PRRX2; MED24; PHF20; TCF7L1; JARID2; RXRG; GFI1; HMGB3; KAT7; EYA1; PHOX2B; HDAC1; C1D; HMG20A; BCOR; FOXO3; ZNF189; RBPJ; SP140; VGLL4; RHOA; ENO1; ATF1; HDAC6; CCNA2; SMARCE1; MYT1L; SMARCA4; ARNTL2; KDM2A; PQBP1; EDF1; BATF; FOSL2; CITED1; YBX1; HSBP1; ING2; HOXD3; EGR4; TSG101; BTF3; HIF1A; HDAC2; BASP1; ZNF281; PFDN5; BBX; SMARCC1; ZBED4; CCNC; TSC22D3; REST; SMARCA5; FUBP1; HOXD1; ZNF532; MED21; CREG1; NCOA6; LZTS1; DNMT3B; CDK7; SCAND1; PITX2; NCOA2; HSF2; MAGED1; NONO; SOX10; TBL1X; ZNF529; C1QBP; SREBF1; CTBP2; MYCBP; RBM39; DDX5; NFE2L1; CTR9; STAT4; SNAI2; NFKBIA; TLE4; MEIS1; MYCN; SMARCD3; ZNF83; ZNF160; RUNX3; NR2F2; RBBP4; KDM5D; KLF2; HMGN3; TRIM22; CCNE1; ZBTB18; HLTF; PEG3; ZMYM2