Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29231	Alectinib	GSE70138	NEU	Human	24h	0.37uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	161	CTNNB1; CCNA2; BTAF1; MAFF; NKX3-1; ZNF654; TAF5; TGIF2; ZNF23; MYNN; ZNF394; FOXM1; MAFG; NR3C2; ZNF276; TOPORS; DEAF1; TWIST1; PRMT2; SMARCA2; MKL1; NFYB; STAT5A; CBX6; ZFHX3; RNF141; PBX2; ETS2; TRAF6; CCDC59; DLX4; FOSL2; MLXIP; ZNF467; REL; HLX; FOXJ2; STAT6; CALR; DEK; IRX4; TFAP2C; ZNF217; SIM2; PAX8; BRIP1; TRIM16; MXD1; CREB3L1; TFE3; ZNF764; CBX4; NCOA1; SMAD5; IRF7; LHX2; MEOX1; NFIC; SOHLH2; ZXDC; HOXA1; CDC5L; STAT2; E2F3; PHF1; POU4F1; FOXA2; KLF3; RBL2; DDIT3; PIR; SSBP3; REST; JUP; ZNF557; ECD; ELK4; MZF1; LPIN2; THAP11; CHD3; PURA; MYC; PBXIP1; ELF4; PSMD9; BRWD1; CREM; TSC22D2; KDM5C; AES; GTF2I; RARG; NFE2L2; ABL1; CITED2; PITX1; NFX1; ZNF512B; TRIM29; PIAS3; KLF2; EHF; EGR3; FOXO1; PRKDC; E2F8; SNAI2; KDM5A; GCFC2; NFIX; GTF2IRD1; ZNF552; LEF1; HIC2; LOXL2; PSMC3; TFCP2L1; RUNX3; ARID5B; JUNB; HMGA2; NR2C1; ZNF587; CREBL2; HOXB13; DLX5; LITAF; RREB1; PLAG1; CEBPB; KLF4; STAT4; HOXD1; BCL11B; ZNF281; SOX10; NR1H3; CBFB; TXNIP; TOB1; SPDEF; ZNF131; TRIP6; MECOM; CNOT3; VDR; HOXC10; MYBL1; ATF5; TBL1X; TGFB1; YBX3; IFI16; FLNA; TRIM22; ZBTB18; JUN; MITF; ESR1; CRK
Down-regulation	149	SUZ12; KAT6B; RFC1; ZBED2; HAND1; MEIS2; ZBTB20; MYT1; SP110; PCGF3; TFCP2; MLXIPL; CREB3L2; TCF21; PHIP; NR2F1; MED1; ID4; ZNF611; ZNF250; IL16; ERBB4; ESRRG; CLOCK; CCNC; HMGN3; UBE2I; CREB1; MED24; ING3; BCLAF1; NOC2L; L3MBTL1; ZBTB32; ATOH1; PITX2; PRPF6; FOXK2; NPAT; ZNF473; ZNF34; CNOT1; SIRT2; PCGF2; RFX5; ILF2; TBX3; TCF12; POU2F1; WWTR1; TDRD3; ZNF532; ZNF93; PUF60; ARID1A; PROX1; RNF4; ZMYND11; BTG1; MTF2; MEIS1; RBBP8; SUPT4H1; SPEN; ID3; KMT2A; ZNF430; HEY2; BLM; CHD8; FOXC1; PBX3; ZNF711; SOX11; ZNF302; TOX3; MNDA; ZFPM2; CARHSP1; ID2; MYCN; HOXB6; FOS; MED17; CTBP1; PSPC1; GTF3A; TULP3; BRD8; FHL5; CITED1; NCOA6; NR4A2; TCF15; SOX9; KLF11; INSM1; HMGB1; SMARCA1; BAZ2B; NEUROD1; YAP1; ZNF432; ERBB2; BASP1; ZNF43; OSR2; NR1D2; CRY1; DACH1; CHD9; ZKSCAN7; BATF; PAX6; CEBPD; APEX1; ZNF551; CAMTA1; ZNF195; VGLL4; DNMT3B; ZEB2; KLF6; CHD7; PBX1; ZNF292; ZNF24; TBL1XR1; PQBP1; PLAGL1; STAT1; HOXB7; ZNF91; TAF9; MAFB; SALL1; ZNF12; ARID4B; SSBP2; INSR; MSX1; FOXJ3; ZNF232; KDM5D; ZEB1; FOXG1; ZNF423; TOX; PEG3