Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29229	Alectinib	GSE70138	NEU	Human	24h	3.33uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	80	BHLHE40; ZNF274; TLE1; SATB1; RNF4; PIAS1; PHF20; NCOA1; NR2E1; NLK; CBX5; YWHAB; FOXA1; ZNF302; MED24; PFDN5; PAX5; ZNF443; ID2; CUX2; TCF12; ZBTB18; TRIM32; TGIF1; CBX3; ARNTL; HLF; RORA; ZBTB16; TSC22D1; LEF1; ZBED4; SOX9; ADNP2; MAFB; SUB1; ABL1; TBX3; NEDD8; FOXG1; MXI1; NKX3-1; ATF5; HMGB1; BRD3; TBL1X; ZNF83; RBBP4; ZNF91; MBD2; HMGB3; IKBKAP; ZNF432; ZNF43; ZFP36L1; BASP1; MAGED1; CBFB; NR2F2; HEY1; APEX1; MKL2; CEBPB; HIRA; FOXJ3; PUF60; HMGN3; TCF7; MSX1; ZNF589; DMTF1; ZMYM2; ZMIZ1; KDM5D; MAF; SSBP2; NRIP1; MTF2; SOX11; CRK
Down-regulation	83	OSR2; MTA1; TBX10; KLF4; FOXL2; ZNF175; TTF2; NR4A2; FOSB; KAT6B; TAF1A; SRCAP; FOXM1; PSMD9; HOXB6; HOXB5; FOXI1; IRF1; TFAP2A; DLX2; HOXB2; SIM1; CCNH; TEAD4; SERTAD2; SNAI2; ESR1; LIN28A; NFE2L2; EHF; WNT4; MYBL2; ATF3; BARX1; NFE2L3; PSIP1; OVOL2; CNOT3; TCF21; VDR; FOXA2; HOXB7; HLX; HDAC9; GRHL2; KLF6; FHL2; SOX17; SOX10; ELF3; GFI1; WT1; TRIM16; BNC2; IRF4; EMX2; VGLL1; KLF11; TFAP2C; CITED2; PBX3; HOXA1; ST18; ELF4; TWIST1; SIX1; FOXF2; HOXC10; RUNX1; GATA6; SLC2A4RG; KLF2; TXNIP; CCNE1; TGFB1; NFKBIB; ZFPM2; ID1; NR1H2; MECOM; NFATC3; MYB; MITF