Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29201	Dabrafenib	GSE70138	NEU	Human	24h	1.11uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	146	USP21; PAX8; SETDB1; ZNF8; MTA1; ZNF212; NEUROG1; PMF1; ZSCAN5A; ZNF384; ZMIZ2; TFAM; NRL; APBB1; KAT7; RFX5; ELF2; SREBF2; ACTL6B; ZFHX3; HMGA1; ARID5B; ARNTL; SIX6; ZNF536; WWC1; NKX3-1; SMARCA2; ETV4; MYRF; TFEB; NFYC; LHX3; SUB1; UBP1; LIMD1; CAMTA2; HR; OLIG2; CDC5L; CBX4; E2F2; SIAH2; HOXB13; ZNF711; TSC22D1; MED15; IL16; LITAF; ZNF410; MYT1; MLX; ARID5A; ARID1A; SPIB; SMAD2; POLR2A; MEOX1; FOXC1; NLK; SETD2; MAZ; RORA; NR3C1; TADA3; RYBP; ZNF444; FOXJ2; MDM4; BCL6; ZNF281; PHF20; CHD8; SREBF1; SATB1; SMARCD1; GRHL2; HMG20B; FOXF2; ZBED2; KLF5; SOX9; PRDM1; EHMT2; CERS6; MTDH; RERE; CREB5; ABL1; SHOX2; SIX3; BRD2; ATF3; CRY1; MYT1L; NEDD8; ZEB2; YEATS4; BASP1; SAP18; HDAC9; RBPJ; NKX2-1; RBPMS; NCOR2; ELK3; NR2F2; KDM5D; HDGF; HSF2; ATF4; AES; DAXX; BHLHE41; ZNF580; POU2AF1; SSBP3; HLF; IRF6; IRF8; ZFP36L2; CBX6; CAMTA1; MKL2; BCL3; PCGF2; FOXJ3; DNMT3B; TWIST1; BAZ2B; HOXC10; DMTF1; SSBP2; TBX3; TOX3; NR1D2; AFF1; HMGN3; DACH1; ZMIZ1; ZMYM2; TXNIP; PSIP1; TRIB3; RELB; NRIP1
Down-regulation	123	KAT6B; HBP1; DLX2; SNAI2; BCL11A; ZNF573; TFDP1; DNAJC2; TCF7L2; HIC2; TAF10; PIR; REPIN1; TCEB2; TBX1; ZKSCAN1; SOX3; PRPF6; LIN28A; GATA4; EYA2; HTATIP2; ELF5; NR4A2; TTF1; IFI16; TGIF2; MXI1; NR1I2; ZNF224; WT1; REL; PRRX1; ZNF562; ZNF426; PSMC3; PLAGL1; MAFB; EMX2; ZNF107; NFX1; TRIM27; BCL10; ZFP30; CCNE1; SOHLH2; PLAGL2; ZNF264; ZNF136; ZNF124; TCF7L1; FLI1; ZNF394; ZNF611; NFE2L2; PHIP; FOSB; BTG1; RNF141; EDF1; ARNTL2; CCNC; CTR9; GLI3; SMARCA1; KLF4; EGR3; KLF10; WWP1; HOXD1; PNRC1; EHF; CITED2; ZNF160; MYB; TCF21; KLF2; DLX5; RAN; ID3; DDX5; ZSCAN18; TAL1; ID1; ZBTB43; TRIM22; MEIS1; HSBP1; ZNF652; CENPF; REST; FOXO1; ZNF721; ISL1; LOXL2; NR0B1; ZNF32; WWTR1; TFDP2; ZNF274; ZBTB20; RUNX1; SOX17; ZNF430; PBX3; NFATC4; SP100; FLNA; NFKB2; ZFPM2; SMAD6; PBX1; HMGB3; EGR1; IRF4; PPARG; PEG3; MAF; AEBP1; MYBL1; ZNF131; ZNF91; NFATC3