Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29199	Dabrafenib	GSE70138	NEU	Human	24h	10uM	EID0123

Response Information :

Types	Number	Response transcription factors
Up-regulation	149	YWHAB; DNMT3B; HMGXB4; TAF5; TAF9B; ZMYND8; HDAC1; KMT2A; ZNF148; EMX2; PBRM1; HDAC6; ASCL1; NUP62; ASH2L; WWC1; HMGB3; TULP4; KDM5B; NANOG; CENPB; MAFG; SMARCE1; PCGF2; PIAS3; SIAH2; TBP; BHLHE41; TRRAP; PHF1; DBP; NFIX; ZBTB24; SUMO1; PBX3; MAGED1; URI1; ESR1; ING2; HCFC1; KAT6A; CBX5; CTR9; ZHX3; GATA3; NCOR2; SOX2; SAP30; RBBP5; DAXX; MGA; SMARCC1; LEF1; BCL11B; DDX5; SIM2; SOX12; KDM2A; RBBP8; ZNF281; PA2G4; DPF2; HSBP1; ZNF532; ZNF302; KAT7; TP53; SSRP1; HNRNPD; SREBF1; CCNA2; BASP1; GATAD2A; TBL1X; WT1; TCERG1; ETV1; RUNX3; TMF1; NCOA6; CHD3; TSC22D4; CARM1; PBX1; CEBPZ; BNC2; POU2AF1; MAZ; NR1D2; GTF2IRD1; SMARCA1; BRD4; KAT6B; CBX6; DNAJC1; NFKBIA; CBX3; SALL2; JARID2; MED12; BMI1; NFE2L1; MXI1; HOXB2; PRKDC; RYBP; AFF1; ELK3; SMARCD3; ERG; PATZ1; ID1; HDAC2; ZSCAN18; SSBP3; SMARCA5; PSIP1; HOXB7; PITX1; PIR; RBBP4; ZNF587; ARID1A; KDM5D; MTF2; ZBTB38; CREB1; RLF; ZIC1; TOB1; HMGB2; TCEA2; ZNF264; PURA; ID4; CHD7; TOX3; HEY2; TOX; ZMIZ1; PEG3; DRAP1; NRIP1; MITF; HLTF; ZBTB18; PUF60; SOX11; CRK
Down-regulation	176	ZNF813; MED14; HOXB9; PRPF6; BRCA2; YEATS2; TTF2; HOXD1; UBE2L3; ETV6; ETV5; ZNF493; TRIP4; SUPT6H; KLF8; TRIM29; HOXC11; BCL11A; ZNF410; ZNF155; ARID5A; POLR3C; FOXF2; NFE2; TEAD4; EN1; MAFF; HIPK1; ZSCAN5A; TFCP2; YBX3; IRF7; ATOH1; FOXC1; VGLL4; IRF3; DLX2; MXD4; EN2; HOXD9; PITX2; PHIP; SND1; SIX2; TBX19; YEATS4; BRIP1; TP63; ZNF345; E2F8; CDX1; ERF; MED15; PRDM12; AFF2; STAT6; NCOA4; ARID3A; LMCD1; OSR2; ZNF473; PNRC1; ZNF83; TRIM22; BACH1; ILF2; GTF3A; CREB5; JUN; ZNF124; RFX5; PIAS4; THRB; PEX14; ZNF117; ZFP30; KLF4; NR4A3; CBX4; SAP18; NR1H4; IRF9; ZNF468; NR0B1; MYBL1; CEBPD; RARB; THAP10; MYBL2; ZNF112; REL; AES; ZNF350; ACTL6A; TBX3; MEOX1; ZFX; PBXIP1; IRF6; PCBD1; LZTR1; THAP7; CAMTA1; SOX10; CALCOCO1; HIVEP1; PAWR; BCL6; IRF8; ZBED4; HIC2; ELF1; FOXI1; ZNF266; SRCAP; BNC1; HOXA5; TFAP2C; HDAC9; HDAC5; DMTF1; SIX3; TRIB3; SPIB; RUNX1; HEY1; MED17; CDYL; JUNB; ZNF611; SMAD7; BAZ1A; ZNF273; SNAI2; PRRX1; HHEX; PSPC1; JAK2; SATB2; FOSL2; STAT1; ZNF195; KLF6; TFAP2A; SLC2A4RG; ZNF551; ZFP36L2; CNOT2; HLX; MNDA; ZNF593; NR4A1; SMAD4; ZMYM2; IKBKAP; ZBED1; APEX1; VDR; SHOX2; FOXJ3; SSBP2; ZEB1; TRIP6; ELF5; GATA6; LOXL2; NR1H3; ZNF232; ARID4B; SOX17; AHR; ST18; BTG1; EGR2; EGR1; ZNF131