Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29059	Regorafenib	GSE70138	NEU	Human	24h	0.04uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	VDR; PPRC1; SNAI2; ZNF394; SOX9; HMGXB3; ATF3; FOSB; URI1; IRF9; RELA; HOXB5; LPIN2; KLF4; LDB1; ZFHX3; MEOX1; MED12; FOXL2; ELF4; BRD4; GCFC2; ETV4; ZNF623; BCL3; ZNF654; HOXB13; ZNF467; TRPS1; NR1I3; PEX14; NR0B2; NKRF; HOXD1; GATA4; HDAC1; HOXB6; STAT6; REST; ZNF160; ZKSCAN1; MED14; NR1H3; IRF1; CNOT3; PRKDC; HDAC7; E2F3; JUNB; MAFF; ZNF131; MTDH; HLX; SIAH2; SOX17; HAND1; KLF2; CREB3L1; ERG; MECOM; ATF1; GRHL2; GATA3; TFCP2L1; RUNX1; FOXA2; LHX6; NKX3-1; ADRB2; TP63; NPAT; NR4A1; ZFHX4; KLF7; SHOX2; PLAGL1; TCF7; NFKBIA; TFEC; ELF3; SP100; MYCL; FOSL2; ZNF721; OSR2; TAL1; SIM2; KLF10; OVOL2; ETS1; TLE4; EMX2; EHF; RREB1; NFE2L2; JUP; MXI1; MITF; MYRF; FOXD1; ZNF652; KLF5; MYB; HES1; IFI16; EGR3; IRF6; HEY1; MNDA; CRK; PSIP1; HOXB2; TRIB3; ESR1
Down-regulation	99	ING1; BLM; DNMT3B; MAX; MTA1; MLX; ZNF410; NR1H4; ZNF83; ZFP36L1; BATF; NLK; HMGB1; CRY1; RYBP; ZBTB1; ZNF253; SIRT7; PIAS2; CREB3L2; CHD7; OLIG2; TSC22D1; NAB1; ZNF184; GTF3A; ZNF711; MYT1; ZKSCAN7; KDM5B; FOXJ3; RUVBL2; SCAND1; NKX2-2; HDAC2; ATN1; CREB1; ZNF117; ATF5; ZNF551; BMI1; ZNF91; CTBP1; ABL1; AES; BRD3; POU2AF1; ETV5; ZNF43; MYT1L; TRIP6; ZBTB38; KAT2B; ZNF302; HMGN3; PSMC3IP; ZNF211; SIX1; TCF4; ASCL1; ZBTB18; PAX6; BIRC2; RFX5; ZMYND8; CITED2; ING3; SATB2; UBE2I; TBX2; ZNF331; ARID4B; BTG1; SUB1; WWC1; RBBP4; BAZ2B; HHEX; PITX2; ZMYM2; ZBTB20; CITED1; CHD9; IRF8; ID2; NR1D2; ZEB2; ZBED2; ZBTB16; DAXX; AEBP1; ZFPM2; INSM1; SOX11; SSBP2; CARHSP1; HOXA5; KLF9; BASP1