Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29054	Regorafenib	GSE70138	NEU	Human	24h	10uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	KMT5A; SMARCD3; PHF2; XBP1; GTF2IRD1; MSX1; FOXK2; PBX2; MAX; ZNF692; COPS2; DNAJC1; TCERG1; PCGF2; TSC22D3; TCF20; NCOR2; ETS2; ZIC1; ZNF189; EHF; SOX2; C1D; TAF9B; HSBP1; CREB3L1; BAZ1A; MED21; WHSC1; MED12; MAML1; BAZ1B; TCEA2; FLNA; DAXX; HDAC2; ING2; PITX1; SMARCA5; SETD2; BATF3; PRRX1; MSC; NRBF2; SIM2; ZKSCAN1; HLTF; HDAC6; SSRP1; VEZF1; SMAD2; CDK8; ZFHX4; PQBP1; MAFG; PAX9; LEF1; FHL2; ZBTB1; SMARCA2; ZMYND11; ATF1; BCOR; PHF1; ARID4A; JARID2; E2F3; SREBF1; BCL11B; SIAH2; GTF2I; ENY2; PBRM1; PATZ1; BMI1; CERS6; DEAF1; NFKBIA; PCGF3; BRD3; EYA2; MXD1; RARG; ZEB1; BHLHE41; GATA3; REST; EYA1; ABL1; ATF2; FOXO3; ADNP; NR2F1; SIX1; KMT2A; EGR2; TULP4; PLAGL2; NKX2-2; CHD4; MAZ; NKX3-1; HOXC6; NR3C2; HDAC1; SMAD7; MTF2; NONO; VGLL4; ARID4B; ZMYM2; RERE; TRIP6; FOXD1; NR1H2; MTA1; HOXC10; TWIST1; FOS; HOXB7; PSPC1; ID1; SPEN; MITF; PURA; BASP1; EGR3; MAGED1; CEBPB; RBBP4; PUF60; RUNX1; MYB; PSIP1; ZMIZ1; TOX; NRIP1; HEY1; KDM5D; WT1
Down-regulation	150	DNMT1; PNRC1; ZNF493; CRYM; KAT6A; ZNF557; ZKSCAN4; ZIC3; ZNF223; ZNF141; IRF8; NR1H4; LITAF; HHEX; CDK2; LOXL2; ZNF254; ZNF682; ZNF813; TAF1D; ARL2BP; NR5A2; SRY; NR1H3; ZBTB3; ZNF257; AES; SCAND1; PIAS4; LIN28A; TFEC; E2F8; ST18; ZKSCAN3; MED14; EN1; HMG20B; TRIM33; BACH2; ZNF180; JUP; ZNF544; SIM1; CREB1; ZNF235; MEOX2; TCF7L2; ZNF8; ACTL6A; MYBL1; MYNN; ZNF611; ZNF14; ZNF345; NEUROD1; UBE2B; HBP1; THAP11; NR2F6; RBBP7; IRF1; IRF9; IRF6; ZNF112; FOXN3; PIAS1; KLF6; ZNF239; GATA6; ZNF44; TAF4B; ZSCAN16; HMGA2; PBX1; ZNF551; LHX3; MAF; XRCC6; STAT6; STAT4; BCL11A; CCNC; ZNF665; ZNF160; FOXJ3; TGIF1; ARNTL; ZNF468; CEBPD; VGLL1; USP16; YBX3; FOXO1; MDM4; PHIP; TFAP2C; ZNF415; MKL2; PEG3; SP140L; WWP1; NKX2-1; CREM; HMGN3; ZNF83; SPIB; HMGA1; KLF10; ZSCAN18; ZNF304; SOX17; CDYL; ISL1; ZNF331; EZH1; ZNF217; PBXIP1; DLX2; ZNF329; TCF7L1; SSX1; MXI1; BNC2; JUNB; SUB1; RBPMS; TRIB3; DMTF1; RFX5; TAL1; GTF3A; HDAC9; ZNF721; HOXD1; THAP10; BTG1; OSR2; AHR; CITED2; ERBB2; MDM2; MYCL; SSBP2; ZBED2; ZNF131; NR4A2; ZFPM2; KLF2; ZNF423; HOXB2