Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29009	Alectinib	GSE70138	NEU	Human	24h	0.37uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	47	TCFL5; SMAD1; ATF3; PEG3; KLF10; MAFB; ZFP36L1; WT1; HHEX; BRD4; AR; YBX1; HOXB6; ZNF112; DAXX; RXRA; NEDD8; ZBED2; NR2F2; WWP1; BRD2; CHD4; SCAND1; PAWR; FOXD1; KLF6; MEIS1; WWTR1; ZFPM2; YBX3; PURA; TRIP6; KLF4; PBX3; CREB1; VGLL4; CEBPB; CARHSP1; APEX1; EYA1; HOXB2; ZNF131; SSBP2; ZNF423; MTA1; SPEN; BASP1
Down-regulation	69	BLM; ASCL1; ELF1; TP63; FUBP1; KMT2B; HBP1; FOXK2; STAT4; DEK; NKX2-1; BCL3; RXRG; NRF1; BCL11B; ZMIZ2; HMGB1; CDC5L; PSIP1; TTF2; MTF2; SP140L; CRY1; SP2; CHD1; ARID4A; ZNF24; NPAT; PAX5; MED13; NR2C1; HOXA1; LEF1; CEBPD; IL16; JAK2; NR1D2; SPIB; ZNF266; POU2AF1; ELF5; IRF4; CBX7; POU4F1; ARNTL; AEBP1; FOXA2; KLF2; SIM2; DLX5; RFX5; TGIF1; ETS1; FOXG1; ZNF430; MYBL1; SOX10; KLF13; ZNF721; ZHX2; ARID4B; IRF6; KLF9; JARID2; RBL2; TRIM22; KDM5D; HOXA5; TWIST1