Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29008	Alectinib	GSE70138	NEU	Human	24h	1.11uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	RELB; PPARG; SUV39H1; BCL3; OLIG2; SPIB; SATB2; EN1; CREB5; HDGF; GTF3A; HMGB1; MYCN; LPIN2; SOX9; CRYM; ZNF22; YBX1; HOXC10; ERBB2; PQBP1; TCEB2; NR1H3; TSC22D1; RNF10; ZNF580; NFE2L3; TCF7; TCF7L2; ZBED2; HHEX; RXRA; MEOX2; TLE4; SSBP2; MNDA; ERF; DLX2; CEBPD; ID3; CEBPB; TAF10; BMI1; DMTF1; ZEB1; SALL1; FOXG1; ID4; RFX5; ZMYM2; APEX1; HEY1; VGLL4; ZBTB18; BASP1; TBX3; ARID4B; ID1; PSIP1; TRIB3
Down-regulation	73	WNT4; JUN; HOXA11; CITED2; ZNF264; GLI3; SOX17; ESR1; ZSCAN31; MEIS1; TP53; JUND; BTG1; STAT4; CHD3; NCOA3; TOB1; DNMT3B; ZNF611; EYA2; ZMYND11; CDK9; NR4A2; TMF1; JUP; GRHL2; SMAD1; PRMT2; ZNF331; MXD1; RORA; LEF1; PITX1; ETS2; ZNF652; RUNX1; CUX1; ATF6; BNC2; IFI16; MITF; KLF6; YAP1; HOXB2; ADRB2; BCL11B; KDM5D; ZMYND8; WT1; AEBP1; TULP4; PAWR; ZBTB38; VDR; ZNF165; IRF6; SMARCA5; FOXD1; SKI; RCOR1; MDM2; MAF; ELK3; TXNIP; MEIS2; HOXA5; RREB1; ELF3; NFE2; GATA6; ATF3; TWIST1; PEG3