Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID29007	Alectinib	GSE70138	NEU	Human	24h	3.33uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	74	NFATC3; ZNF426; ZKSCAN1; MED15; ZNF551; TOX3; TFAM; SATB2; THAP7; ZBED4; MTDH; CREB3L2; MXI1; TMF1; REPIN1; ZNF148; IRF9; CERS6; RNF138; SIX1; ZNF124; WWTR1; PEG3; INSM1; ZNF652; CREB3L1; DACH1; ZBTB20; PAX6; ATF2; JUN; AHR; PBX3; SP110; PHIP; HOXB6; ASCL1; SSX1; MYCBP; NKX3-1; NCOA4; HOXC10; NR1D2; ZNF432; SMAD5; TCF21; HIC2; ZEB2; SIM2; BMI1; HOXC6; POU2AF1; LEF1; MED24; CREG1; SOX9; BTG1; CHD9; CD3D; LITAF; EYA1; NR2F1; BAZ2B; HEY1; SSBP2; ATF4; SPEN; RFX5; PSIP1; MEIS2; CARHSP1; HMG20B; PUF60; TRIB3
Down-regulation	66	TAF5; ZNF286A; NKX3-2; BCL6; CREM; NFYB; ZIC3; GCM1; COPS2; TP63; NPAS1; TCEB2; BCL11A; ZNF331; HOXA1; RBBP8; PBX1; HOXD3; PREB; ASH2L; FOXC1; TFAP2C; TFAP2A; TAL1; TGIF2; ZNF532; NFE2L1; TSC22D3; RAN; PRRX1; INSR; STAT4; NR2C1; NFATC1; ELF4; TERF2; EYA2; LIN28A; CUX1; FOSB; ZBTB16; AEBP1; HMGB1; RORA; ZNF281; CCNE1; CDK7; RBPJ; LOXL2; RUNX1; ZNF232; RUNX3; HLX; SOX10; FOXJ3; KLF9; ID1; ZMYM2; SMARCA5; ZFP36L2; TRIM29; TSC22D1; ZNF423; ID4; ID3; KDM5D