Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28981	Dabrafenib	GSE70138	NEU	Human	24h	0.04uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	TOPORS; KLF10; NFATC3; ZNF264; TCF12; TCF4; FLNA; CSDE1; HMGB3; PTRF; SMAD7; ZFHX4; NKX2-1; ZNF532; INSM1; CNOT1; MED17; SALL2; NFIB; RNF138; ATF3; BCOR; PBRM1; MAGED1; ZKSCAN7; ESR1; BIRC2; NR3C2; ASH2L; WT1; MAF; DDX5; SIX2; TLE4; CHD7; RUNX3; TOX3; EYA1; FOXO1; ZBED2; MECOM; EGR3; SSBP2; DLX2; NR4A2; SPEN; RFX5; PUF60; PSIP1; DACH1; ZMIZ1
Down-regulation	68	HMGA1; ZFP36L1; NR2F6; MYC; KDM5A; NR1H4; PITX1; HNRNPD; KLF3; ZNF93; ZHX2; CAPN15; FOXJ3; SIM1; LHX3; TGIF1; SOX13; HOXB7; SPDEF; HDGF; GTF3A; RNF6; IRF3; HHEX; AIP; ARNTL; SLC2A4RG; ZNF721; TAF10; DDIT3; INSR; IRF1; BATF; FOXN3; ELF4; ATN1; CEBPB; TBL1X; RUNX1; PBX1; DMTF1; ZNF160; TEAD4; ELK3; PRRX1; TRIB3; MNDA; HMGB2; TRIM29; ZBTB38; SSX1; ZMYM2; AEBP1; JUNB; IRF4; WWTR1; ZNF91; LOXL2; SALL1; TFAP2C; MYRF; PITX2; YBX3; KLF9; IFI16; ARID4B; EGR1; TRIM22