Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28978	Dabrafenib	GSE70138	NEU	Human	24h	1.11uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	102	ZNF84; SATB1; RLF; MYCN; IRX5; ZNF573; RNF14; ZNF410; SMARCA2; PCGF2; ZNF587; TOB1; SIAH2; ADNP2; ZBTB11; MAX; GABPB1; RNF10; HSF2; HDAC2; PAXBP1; TSC22D2; CITED2; ZBTB1; RYBP; ZNF263; TSC22D1; ISL1; TCERG1; JUND; SATB2; DNMT3B; SAP18; ZNF160; RBBP4; DMTF1; HSBP1; MED1; TOX; TCF25; ZNF544; SAP30; ZNF146; RAN; MYT1L; SMAD2; ZNF12; RNF4; ERG; BCLAF1; ZEB2; NCOA4; CHD9; DEAF1; ZMYM2; NEDD8; ADNP; GATAD2A; ZBTB20; PITX1; ZNF131; TCF7L2; JARID2; ZNF83; PBX1; SMARCD3; TAF9B; ZNF711; MXI1; PAX5; EGR3; FOXJ3; MAGED1; HOXC6; RNF138; PATZ1; ARID4B; EYA1; ZNF721; TLE4; ATF4; CREB1; RCOR1; HTATIP2; SSBP2; TOX3; LITAF; HLTF; ZNF91; NR4A2; APEX1; HMGN3; RUNX3; TBX3; VGLL4; BASP1; PSIP1; TXNIP; NRIP1; KDM5D; ZMIZ1; PUF60
Down-regulation	134	GMNN; CDK2; RORC; NFE2L3; TRIP11; CRYM; ZNF816; ZNF215; PRDM2; LHX3; NR5A2; EMX1; PCBD1; HNF4G; HIPK2; ZNF557; IRF6; ASCL3; KDM5C; SSBP3; MAK; NR0B2; IKZF3; ZNF835; TTF2; TEF; FOXJ1; ARID3A; E2F8; NKX2-1; HSF1; BNC1; SRCAP; PRDM12; BLM; KLF15; TP53; ATN1; ZNF257; SP100; PNRC1; FOXE1; ZNF552; CBX7; OVOL1; MAP3K10; CALCOCO1; CENPB; SOX9; TEAD4; SIM1; NR2E1; RORA; FOXN3; YAP1; GLI3; CDIP1; PRDM1; IFNB1; LOXL2; CREB3L2; HOXB2; SKIL; ETV4; PGR; EMX2; CEBPD; ELF4; IKZF1; NR1I2; BNC2; VDR; PBX3; SREBF1; PDLIM1; RFX5; HMGA1; FOXA2; ZIC1; MEIS2; KAT6B; MYBL1; KLF10; SOX21; VGLL1; PPP1R13L; NEUROD1; GATA6; SOX17; HOXC8; MYRF; ZBTB16; CAMTA2; FOXI1; SPEN; JUNB; IL16; KLF4; ZNF217; TFEB; FOXM1; THAP10; HOXD1; KLF13; IRF7; DAXX; NFATC4; GATA1; KLF6; PITX2; TDP2; SNAI2; STAT4; SOX10; PIR; AEBP1; GFI1; ST18; IRF8; PTTG1; TRIB3; HDAC9; RUNX1; ZFPM2; TFAP2A; DLX5; TGFB1I1; ESR1; YBX3; ZBTB18; TWIST1; ID3; HEY1; MECOM