Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28977	Dabrafenib	GSE70138	NEU	Human	24h	3.33uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	PPARG; EPAS1; NFATC3; MNAT1; TCFL5; MYT1L; BACH2; EBF2; MEOX2; ARID5B; BRD3; HOXC6; ARID4A; ELF5; TRIP4; NFIB; PSPC1; ATF5; NKX2-1; ERG; TAF9B; ZNF227; HSBP1; MED1; MGA; ZNF146; FHL5; ZNF148; ZNF189; COPS2; ZFHX4; ZNF589; ABL1; ATF4; PTRF; ZKSCAN7; EDF1; PATZ1; ZNF292; SFPQ; FOXE1; TRAK1; KDM5A; ID2; MYCL; CNOT1; UBE2B; CDYL; TBL1XR1; CNBP; PRDM10; NR1D2; RYBP; ID1; ZBTB20; ZEB1; HMBOX1; SF1; HIC2; BBX; HLF; ZBTB1; ASCL1; BCOR; PQBP1; RBBP4; ZBTB16; SIM2; CERS6; TOX3; SSBP2; CUX1; ZMYM2; TP63; KLF5; CHD9; RCOR1; EHF; PITX2; PCGF2; DMTF1; DACH1; ZFPM2; TBX3; PSIP1; ZIC1; ZNF131; ZNF423; MAGED1; ARID4B; TRIM29; HEY1; INSM1; MTA1; SPEN; TRIB3; ZMIZ1
Down-regulation	67	MEIS1; ZNF394; ZNF331; IRF5; SPDEF; NFIC; C1D; YBX2; FOXJ1; KDM5D; CCNE1; HOXC4; LITAF; RORA; TRIP6; HIPK1; ZNF136; E2F8; SOX9; TTF2; RBBP8; CITED2; NR4A2; ZNF415; GATA3; SIX3; IRF3; SREBF1; ATF3; IKZF1; NFIX; TFAP2A; FOSB; NR0B1; JUND; WT1; NFE2L2; BCL11A; HDAC9; LOXL2; PITX1; CEBPB; PDLIM1; TFAP2C; ELF3; HMGA1; FOSL2; SIX2; HOXB2; NR1H2; VDR; IFI16; NKX3-1; FOS; ESR1; KLF2; MYB; MNDA; NFE2; MYBL1; OSR2; TSC22D1; MYBL2; EGR1; DLX5; HOXA5; E2F2