Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28976	Dabrafenib	GSE70138	NEU	Human	24h	10uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	140	GATA3; MEF2C; MYCN; IRX5; MNAT1; NFATC3; FLNA; CEBPZ; RLF; TAF1D; BRD3; ZNF84; SATB1; MED6; RXRA; PKNOX1; SMARCC1; HIVEP2; NCOA1; CITED2; GLI2; ZNF267; WDHD1; TBL1XR1; TLE1; RORA; NR2F2; KAT2B; PMS1; PSPC1; SAP18; CHD1; AATF; ZBTB1; PAXBP1; FOXJ3; PCGF2; HOXC6; RBBP4; ZNF24; USP16; FOXC1; ZNF226; KLF5; NFYC; NUP62; TCF7; USF2; ARID4A; ZNF160; ZNF146; SOX9; CUX2; ZNF443; CBX3; KMT2A; TBX3; ATF7IP; ADNP; BCLAF1; SATB2; TRIM32; HEY2; DNAJC1; ID2; CTBP2; ETS2; ZNF184; MAFB; BATF3; RNF10; ERBB4; SIAH2; BACH1; ZNF263; VEZF1; SIX1; BTG1; BRD8; SMAD2; ABL1; NCOR2; SUPT4H1; CARM1; TERF2; ZNF292; HMG20A; BAZ2B; ZMIZ2; PQBP1; HOXC10; EYA1; BMI1; TSC22D1; PBX1; ARID4B; SAP30; BCOR; ZNF302; SCAND1; MAGED1; BCL11B; JARID2; HDAC4; HSF2; BPTF; ERG; ZNF721; ZMYM2; TRIM16; MYCL; IKBKAP; RCOR1; TBX2; TOX3; MTF2; ZBTB18; TCF4; ZBTB20; VGLL4; NFAT5; MED1; HTATIP2; MYB; CREG1; RFX5; CHD9; TRPS1; ZNF131; SPEN; SSBP2; ZNF32; MSX1; APEX1; NRIP1; ZNF423; ZMIZ1; PUF60; ID3; HMG20B
Down-regulation	164	CDK2; JUND; ZNF623; ZFPM2; ZNF415; MYC; DNMT1; PRDM14; TULP2; JUN; ZNF264; TAF4B; NEUROD2; PAX2; HOXB1; TTF2; ZNF215; ZNF835; FLI1; MAFF; MLLT1; TCF7L1; SPDEF; ZNF528; ZXDB; BRDT; SOHLH2; POU4F3; TP73; HOXB2; SOX14; ZNF816; MKL1; ZNF552; AFF4; FOXF2; IL16; SRY; SOX1; ZNF667; GRIP1; ATN1; ZNF695; NEUROG2; TLX3; GBX2; SSX3; ALX4; TEF; ZNF442; SCRT1; CHD2; SRCAP; CDIP1; VGLL1; SPI1; HNF1B; C1QBP; HOXB8; ZNF749; PROX1; TFDP3; LYL1; HOXD12; ZNF354A; TRIM24; HAND1; CDX4; BNC2; TULP1; NEUROD1; ETV6; LHX3; IFI16; SNAI2; NFKB1; NFX1; LEF1; POU1F1; EMX2; NR2E1; SPIB; PITX1; ARNTL2; AIP; THRB; GATA4; ANKRD1; ELK3; MXD1; ARID3A; BNC1; FOXM1; ST18; ZNF165; EPAS1; ATF3; VDR; HSF1; TRIM22; ARNT; MLXIP; IFNB1; LMCD1; CALR; HMGA1; HLX; SSX1; CITED1; SP100; SOX17; SMAD1; ELF4; EGR4; NR4A3; SOX21; NFATC1; ZNF778; SP140L; NFIC; NFATC4; SOX10; EGR2; TLE2; DDIT3; RUNX1; AEBP1; SKIL; EHF; FHL2; PSIP1; PTTG1; BARX1; FOXA2; GATA2; PGR; MITF; ZNF43; NR1H2; NFE2; WWC1; PDLIM1; PEG3; ZNF512B; ELF3; IRF6; LOXL2; BHLHE41; WWTR1; RBPMS; ZFP36L2; MDM2; HDAC9; ZBTB16; WT1; CCNE1; HOXA5; MECOM; MEIS1; E2F2; PIR; DLX5; RELB; KDM5D