Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28896	Saracatinib	GSE70138	NEU	Human	24h	0.37uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	ZNF177; LPIN2; ZNF200; ING2; COPS5; HABP4; TAF1A; HIF1A; EP400; E2F2; CREB5; ERG; RRN3; ZNF267; PRKDC; FOXF1; BACH2; SREBF1; SMARCC1; ASXL1; CREBZF; ZNF281; GABPB1; ZFHX4; ZNF443; BANP; ZSCAN32; ANKRD1; SMARCA1; SMAD6; ZBTB11; NRBF2; E2F6; CTR9; DDIT3; CNBP; E2F5; EPAS1; EDF1; CENPF; DLX4; ZNF227; NKX2-1; DDX5; NR3C2; TAL1; KMT2B; KMT2A; NR1I2; TULP4; VDR; WWP1; MYBL1; SMARCD3; ZNF226; TTF1; PAXBP1; IRF1; RORA; MKL2; DMTF1; CDK7; ZNF189; GTF2IRD1; HMBOX1; SMARCA5; TAF9; ZNF430; ZNF131; MECOM; MYT1L; PLAGL2; BCL11B; FLNA; FUBP1; MAFB; ZMYND8; HLTF; HOXA5; MSX1; ARID4B; ABL1; IFNB1; DNMT3B; LEF1; SMAD7; NR0B1; CARHSP1; ZNF160; SPEN; TBX2; GATA1; NFKBIA; HEY2; ASCL1; PITX2; ARNTL; ZNF165; ID1; TOX3; TGFB1; ID3; RBBP4; FOXJ3; VGLL4; KLF2; WT1; TRIB3; BASP1
Down-regulation	132	CDK2; IRF9; CRYM; TRIP6; ZNF264; NAB1; AR; ZIC3; SRF; LMCD1; ZNF787; RING1; TRIM29; IRF3; ZIC1; ADNP2; LZTR1; POU2AF1; MNX1; HDAC6; AES; YBX3; AIP; SHOX2; ATF5; FOXJ2; FOXN3; IRF5; TFAP2C; ERCC3; SP2; C1D; PFDN5; CENPB; NFIC; CCNC; ERBB4; ESRRA; COPS2; ZNF444; ARNTL2; CDYL; ZNF528; SOX15; ZNF768; TGIF1; ETV5; IL16; INSR; TCF20; IRF6; HOXB2; PCGF3; FOXA1; CBX7; ZNF580; KDM5A; PQBP1; TP63; SIX2; TRPS1; HNRNPD; RFXANK; SSBP2; ARL2BP; THAP10; ST18; CNOT2; SP3; EHF; ATN1; SOX10; ZNF124; SUB1; JUND; JUN; LIN28A; ZNF432; MYCL; SPIB; KLF6; RUNX3; LOXL2; RFX5; CD3D; CREG1; SALL2; NR2F6; SFPQ; MSC; NEUROD1; PPP1R13L; HMGN3; CALR; FOXF2; IRF4; MNDA; NR2F1; SIX1; TGFB1I1; HDAC4; RUNX1; CITED1; EMX2; TOX; MITF; TCF4; WWC1; BCL11A; DACH1; PSIP1; PTTG1; NKX3-1; AEBP1; IRF7; DAXX; BTG1; TOB1; TCEA1; ATF3; ZNF217; ZMYM2; NR4A2; SNAI2; ZFPM2; BHLHE41; TXNIP; MTA1; KLF9; TRIM22; KDM5D; GATA6