Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID28893	Azd-7762	GSE70138	NEU	Human	24h	0.12uM	EID0122

Response Information :

Types	Number	Response transcription factors
Up-regulation	79	FLI1; E2F2; NR0B1; SMAD2; HAND1; ZNF573; MNAT1; MYT1L; SSBP3; ONECUT2; BMI1; TBX2; PMS1; RBM39; STAT1; PIAS1; ZMYND8; ARNTL2; ANKRD1; HOXC6; ZBTB1; NKX2-2; MNT; ELF3; RNF10; ZNF184; TFDP2; PHF20; SATB2; TAL1; MXI1; NR1I2; LPIN2; NEUROD1; ZNF267; BAZ1A; PITX1; BRD3; ZNF189; ZNF131; INSM1; STAT4; SAP30; CTBP2; RXRA; BATF3; ZEB2; AFF1; ZNF281; E2F5; NKX2-1; HDAC4; BBX; PATZ1; ZBTB20; BCL11B; CREB1; MTF2; CTBP1; RCOR1; RBBP4; SIM2; TBL1XR1; MYB; CARHSP1; MNDA; SSBP2; TLE4; VGLL4; BASP1; CBX6; MAFB; ZNF423; HOXA5; ARID4B; PSIP1; ZMYM2; TRIB3; ZMIZ1
Down-regulation	73	JUN; POLR2A; LEF1; CALR; ENO1; KAT6A; ELK4; RELA; CNOT3; ZBED1; BCL6; TP53; HMGA1; ZNF516; SLC2A4RG; SPEN; ZNF468; SIRT7; SSRP1; MYRF; YAP1; FOXC1; SP2; ZFHX3; SIAH2; FOXM1; PPP1R13L; JUND; MED14; AHR; MED15; BCL3; TRIM28; ARID1A; NR4A1; ZNF593; ZNF552; HDAC9; NANOG; SOX17; CHD8; IRF8; TCF7L1; FOSB; FOXA1; FOXJ1; ZIC1; SF1; TGFB1; SALL1; ADRB2; HLX; CEBPD; YBX3; ERBB4; TGFB1I1; FOXA2; SIX2; NR2F1; IRF7; ELF5; HOXB6; TP63; CITED1; NR1H2; HOXB2; EMX2; NR2F2; RUNX3; KLF4; HEY1; IRF6; SKI